4.7 Article

Increasing Drug Resistance in Extensively Drug-Resistant Tuberculosis, South Africa

期刊

EMERGING INFECTIOUS DISEASES
卷 17, 期 3, 页码 510-513

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CENTERS DISEASE CONTROL
DOI: 10.3201/eid1703.101363

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资金

  1. Doris Duke Charitable Foundation
  2. President's Emergency Plan for AIDS Relief
  3. Burroughs Wellcome Fund
  4. American Society of Tropical Medicine and Hygiene
  5. Gilead Foundation
  6. Howard Hughes Medical Institute
  7. Irene Diamond Fund

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We expanded second-line tuberculosis (TB) drug susceptibility testing for extensively drug-resistant Mycobacterium tuberculosis isolates from South Africa. Of 19 patients with extensively drug-resistant TB identified during February 2008 April 2009, 13 (68%) had isolates resistant to all 8 drugs tested. This resistance leaves no effective treatment with available drugs in South Africa.

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