期刊
ACTA BIOMATERIALIA
卷 6, 期 3, 页码 750-755出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.actbio.2009.08.012
关键词
Carbonate; Electrospraying; Nanoapatites; Osteoblasts; Silicon
资金
- Engineering and Physical Sciences Research Council, United Kingdom [GR/S97873, GR/S97880]
- Ministry of Education Academic Research, Singapore [R-265-000-311-133]
- EPSRC [EP/E045839/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [GR/S97880/01, GR/S97880/02, EP/E045839/1] Funding Source: researchfish
A new deposition method is presented, based on electrospraying, that can build bioceramic structures with desirable surface properties This technology allows nanoapatite crystals, including hydroxyapatite (nHA), carbonate-substituted HA (nCHA) and silicon-substituted HA (nSiHA), to be electrosprayed on glass substrates Human osteoblast cells cultured on nSiHA showed enhanced cell attachment, proliferation and protein expression, namely alkaline phosphatase, type I collagen and osteocalcin, as compared to nHA and nCHA. The modification of nanoapatite by the addition of silicon into the HA lattice structure renders the electrosprayed surface more hydrophilic and electronegatively charged (C) 2009 Acta Materialia Inc. Published by Elsevier Ltd All rights reserved
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据