期刊
ACTA BIOMATERIALIA
卷 4, 期 5, 页码 1536-1544出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.actbio.2008.03.013
关键词
titanium alloys; surface modification; bioactivity; selective electron beam melting; porous structures
资金
- Deutsche Forschungsgemeinschaft (DFG)
Selective electron beam melting (SEBM) was successfully used to fabricate novel cellular Ti-6Al-4V structures for orthopaedic applications. Micro computer tomography (mu CT) analysis demonstrated the capability to fabricate three-dimensional structures with an interconnected porosity and pore sizes suitable for tissue ingrowth and vascularization. Mechanical properties, such as compressive strength and elastic modulus, of the tested structures were similar to those of human bone. Thus, stress-shielding effects after implantation might be avoided due to a reduced stiffness mismatch between implant and bone. A chemical surface modification using HCl and NaOH induced apatite formation during in vitro bioactivity tests in simulated body fluid under dynamic conditions. The modified bioactive surface is expected to enhance the fixation of the implant in the surrounding bone as well as to improve its long-term stability. (C) 2008 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
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