期刊
BIOCHEMISTRY MOSCOW-SUPPLEMENT SERIES B-BIOMEDICAL CHEMISTRY
卷 5, 期 2, 页码 95-102出版社
MAIK NAUKA-INTERPERIODICA
DOI: 10.1134/S1990750811020120
关键词
antimicrobial peptides; mode of action; practical application
资金
- Analytical Departmental Target Program [2.1.1./2889]
This review deals with antimicrobial peptides (AMPs) that demonstrate antibacterial, antiviral, and antifungal activity. It considers structure and mechanism of AMP interaction with lipid membrane and intracellular targets of pathogens. Special attention is paid to modern state and perspectives of AMP practical application and also to approaches that increase efficacy and reduce toxicity of AMP by chemical modification of their structure.
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