期刊
ACS NANO
卷 5, 期 6, 页码 4490-4503出版社
AMER CHEMICAL SOC
DOI: 10.1021/nn1035312
关键词
collagen; gold-coated collagen fibers; stem cell differentiation and proliferation
类别
资金
- Investing in people!
- Sectoral Operational Programme Human Resources Development
- Babes-Bolyai University, Cluj-Napoca, Romania [POSDRU 6/1.5/S/3]
- University of Medicine and Pharmacy, Cluj-Napoca, Romania [41-077/2007]
- Arkansas Science and Technology Authority
- U.S. Army, Telemedicine & Advanced Technology Research Center (TATRC)
Gold-coaled collagen nanofibers (GCNFs) were produced by a single-step reduction process and used for the growth and differentiation of human adult stem cells. The nanomaterials were characterized by a number of analytical techniques including electron microscopy and spectroscopy. They were found to be biocompatible and to Improve the myocardial and neuronal differentiation process of the mesenchymal stem cells isolated from the placental chorionic component. The expression of specific differentiation markers (atrium, natriuretic peptide, actin F and actin monomer, glial fibrilary addic protein, and neurofilaments) was investigated by immunocytochernistry.
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