期刊
ACS NANO
卷 5, 期 6, 页码 4704-4711出版社
AMER CHEMICAL SOC
DOI: 10.1021/nn2006128
关键词
neural stem cells; carbon nanotubes; polarization; nanotopography; micropattern
类别
资金
- NRF [2011-0000390]
- Happy Tech Program [20100020821]
- Converging Research Center program [2010K0-01138]
- MKE
- NIH [1DP20D-006462-01]
- NJ commission on Spinal Cord [09-3085-SCR-E-0]
We report a method for selective growth and structural-polarization-controlled neuronal differentiation of human neural stem cells (hNSCs) Into neurons using carbon nanotube network patterns. The CNT patterns provide synergistic cues for the differentiation of hNSCs in physiological solution and an optimal nanotopography at the same time with good biocompatibility. We demonstrated a polarization-controlled neuronal differentiation at the level of Individual NSCs. This result should provide a stable and versatile platform for controlling the hNSC growth because CNT patterns are known to be stable in time unlike commonly used organic molecular patterns.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据