β-Cyclodextrin-Functionalized Silver Nanoparticles for the Naked Eye Detection of Aromatic Isomers

We report herein the development of a highly robust, quantitative, sensitive, and naked eye colorimetric detection method for different isomers of aromatic compound using beta CD modified silver nanoparticle (AgNPs) probes This assay relies on the distance dependent optical properties of Ag nanoparticles rand the different Inclusion binding strength tithe aromatic guests to beta CD host In the presence of different isomers of aromatic compounds AgNPs could be rapidly Induced to aggregate, thereby resulting In apricot to-red color change The variety and concentration of different isomers of aromatic compounds could be determined by monitoring with the naked eye or a UV-vis spectrometer The present detection limit for different isomers of aromatic compounds is 5 x 10(-5) M We believe that the surface architectures of AgNps after the introduction of the CD based host-guest recognition would be applicable for a range of chemical and bioanalytical molecular sensing systems in aqueous media