期刊
ACS NANO
卷 2, 期 5, 页码 873-878出版社
AMER CHEMICAL SOC
DOI: 10.1021/nn700319z
关键词
silicon; quantum dot; nanocrystal; micelle encapsulation; in vitro imaging
类别
资金
- NCI NIH HHS [R01 CA119397-03, R01 CA119397-04, R01 CA119397, R01CA119397] Funding Source: Medline
Luminescent silicon quantum dots (Si QDs) have great potential for use in biological imaging and diagnostic applications. To exploit this potential, they must remain luminescent and stably dispersed in water and biological fluids over a wide range of pH and salt concentration. There have been many challenges in creating such stable water-dispersible Si QDs, including instability of photoluminescence due their fast oxidation in aqueous environments and the difficulty of attaching hydrophilic molecules to Si QD surfaces. In this paper, we report the preparation of highly stable aqueous suspensions of Si QDs using phospholipid micelles, in which the optical properties of Si nanocrystals are retained. These luminescent micelle-encapsulated Si QDs were used as luminescent labels for pancreatic cancer cells. This paves the way for silicon quantum dots to be a valuable optical probe in biomedical diagnostics.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据