期刊
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
卷 35, 期 3, 页码 545-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.iac.2015.05.005
关键词
Eosinophils; Atopic dermatitis; Drug hypersensitivity reaction; Cutaneous lymphoma; Eosinophilic dermatitis; Hypereosinophilic syndromes
Eosinophil infiltration can be observed in skin disorders, such as allergic/immunologic, autoimmune, infectious, and neoplastic diseases. Clinical presentations are variable and include eczematous, papular, urticarial, bullous, nodular, and fibrotic lesions; pruritus is a common symptom in all. In this review, we present representative eosinophilic skin diseases according to their clinical pattern, together with histologic findings and diagnostic procedures. We also discuss the potential roles of eosinophils in the pathogenesis of dermatologic disorder. Current pathogenesis-based diagnostic and therapeutic approaches are outlined.
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