Orthogonal Ambipolar Semiconductors with Inherently Multi-Dimensional Responses for the Discriminative Sensing of Chemical Vapors

Numerous examples of field-effect transistor (FET) biosensors and chemical sensors with good sensitivity and selectivity have now been developed. However, effectively discriminating between analytes has required either the use of receptors that selectively bind specific analytes or the fabrication of an array of sensors with varying but nonspecific responses. Both approaches exhibit significant limitations. In the first case, it can be difficult to design sufficiently specific receptors for many compounds, whereas the number of receptors required scales with the number of analytes to be detected, making it impractical to recognize many different compounds. In the second case, existing approaches to FET sensor arrays are generally material inefficient and provide modest sensitivity. Here, we demonstrate that orthogonal ambipolar semiconductors consisting of semiconducting p-type polymers and n-type small-molecule nanowires with perpendicular in-plane orientations provide a platform with high sensitivity and inherently multidimensional response. This allows for discrimination between even closely related derivatives such as aromatic isomers and n-alkyl alcohols varying in length by a single carbon atom resolution using only a single sensor element.