CuO Nanoparticles-Containing Highly Transparent and Superhydrophobic Coatings with Extremely Low Bacterial Adhesion and Excellent Bactericidal Property

Human health and industrial instruments have been suffering from bacterial colonization on the surface of materials for a long time. Recently, antibacterial coatings are regarded as the new strategy to resist bacterial pathogens. In this work, novel highly transparent and superhydrophobic coatings with extremely low bacterial adhesion and bactericidal performance were prepared by spray-coating hydrophobic silica sol and CuO nanoparticles. The coated glass showed high transmittance in 300-2500 nm with a maximum value of 96.6%. Compared with bare glass, its superhydrophobic characteristics resulted in a reduction in adhesion of bacteria (Escherichia coli, E. coli) by up to 3.2 log cells/cm(2). Additionally, the live/dead staining test indicated that the as-prepared coating exhibited excellent bactericidal performance against E. coli. Moreover, the as-prepared coating could maintain their superhydrophobicity after the sand impact test. The proposed method to fabricate such coatings could be applied on various substrates. Therefore, this novel hybrid surface with the abilities to reduce bacterial adhesion and kill attached bacteria make it a promising candidate for biosensors, microfluidics, bio-optical devices, household facilities, lab-on-chips, and touchscreen devices.