期刊
ACS APPLIED MATERIALS & INTERFACES
卷 10, 期 31, 页码 25955-25959出版社
AMER CHEMICAL SOC
DOI: 10.1021/acsami.8b09139
关键词
antimicrobial photodynamic inactivation; antibacterial surface; anti-infective polymer; antibiotic-resistant bacteria; antiviral; block copolymer; olefin thermoplastic elastomer
资金
- NC State Nonwovens Institute
- State of North Carolina
- National Science Foundation [ECCS-1542015]
To combat the global threat posed by surface-adhering pathogens that are becoming increasingly drug-resistant, we explore the anti-infective efficacy of bulk thermoplastic elastomer films containing similar to 1 wt % zinc-tetra(4-N-methylpyridyl)porphine (ZnTMPyP4+), a photoactive antimicrobial that utilizes visible light to generate singlet oxygen. This photodynamic polymer is capable of inactivating five bacterial strains and two viruses with at least 99.89% and 99.95% success, respectively, after exposure to noncoherent light for 60 min. Unlike other anti -infective methodologies commonly requiring oxidizing chemicals, carcinogenic radiation, or toxic nanoparticles, our approach is nonspecific and safe/nontoxic, and sustainably relies on the availability of just oxygen and visible light.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据