Thin-Walled Graphitic Nanocages As a Unique Platform for Amperometric Glucose Biosensor

A thin-walled graphitic nanocages material with well-developed graphitic structure, large specific surface area and pronounced mesoporosity was synthesized and used to construct a sensing interface for an amperometric glucose biosensor, showing a high and reproducible sensitivity of 13.3 mu A mM(-1) cm(-2), linear dynamic range of 0.02-6.2 mM, and fast response time of 5 s. It was successfully used to accurately detect glucose in human serum with effective discrimination to common interference species such as dopamine, ascorbic acid, acetaminophen, and uric acid.