期刊
CANCER CELL
卷 40, 期 10, 页码 1081-1083出版社
CELL PRESS
DOI: 10.1016/j.immuni.2015.02.005
关键词
-
资金
- National Cancer Institute awards [4R00CA259223, 1R37CA263320-01A1]
In this study, Wang et al. used whole-genome sequencing to comprehensively analyze common and rare variants associated with lung cancer risk in individuals with East Asian ancestry. Their findings suggest that rare promoter variants in the BRCA2 gene are associated with an increased risk of lung cancer.
In this issue of Cancer Cell, Wang et al. use whole-genome sequencing of lung cancer cases and controls with East Asian ancestry to comprehensively characterize both common and rare variants that predispose to lung cancer. Their findings suggest that rare promoter variants in BRCA2 are associated with increased lung can-cer risk.
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