期刊
ACS APPLIED MATERIALS & INTERFACES
卷 1, 期 3, 页码 532-536出版社
AMER CHEMICAL SOC
DOI: 10.1021/am800251a
关键词
stimuli-responsive membrane; thin polymer film; biocatalytic process; chemical gating
资金
- NSF [DMR-0706209, CCF-0726698]
A nanostructured signal-responsive thin hydrogel membrane was coupled with enzyme-based systems to yield smart multisignal-responsive hybrid systems with built-in logic. The enzyme systems transduce biochemical input signals into structural changes of the membrane, thus resulting in the amplification of the biochemical signals and their transformation into the gated transport of molecules through the membrane. Coupling of the biocatalytic systems with a stimuli-responsive membrane is a promising approach for the development of materials that can regulate transport and release of chemicals/drugs by receiving and processing the biochemical information via biochemical reactions.
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