期刊
INTERNATIONAL JOURNAL OF PRECISION ENGINEERING AND MANUFACTURING
卷 12, 期 4, 页码 695-701出版社
KOREAN SOC PRECISION ENG
DOI: 10.1007/s12541-011-0090-z
关键词
Bone substitute; Hydroxyapatite; Solid freeform fabrication; Porous scaffold
资金
- Ministry for Health & Welfare, Republic of KoreaA091167 [A091167]
- Korea Health Promotion Institute [A091167] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [과C6B2505] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
A novel porous scaffold designed for application as a bone substitute, with a structure containing three-dimensional (3D) pore channels in a hydragapatite (HA) scaffold, was fabricated using a combination of a solid freeform fabrication (SFF) and cast in a mold using freezing casting method. This study was performed to evaluate the physical and biomechanical properties of the HA scaffolds fabricated by SFF and using polymer replication method (PRM), one of the conventional methods. Although the phase composition and porosity of these two scaffolds are similar, their external shape and mechanical property were different. All of the fabricated scaffolds showed similar patterns through X-ray diffraction. The difference between porosities of two HA scaffolds were not statistically significant (P>0.05). However, the average compressive strength of the scaffold fabricated by SFF was 14.6 MPa, and that of the scaffold fabricated using polymer replication was 3.56MPa (P<0.05). It was confirmed that SFF fabrication could have a relatively higher mechanical property than PRM fabrication at the same porosity
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