期刊
ABDOMINAL IMAGING
卷 40, 期 6, 页码 1769-1771出版社
SPRINGER
DOI: 10.1007/s00261-014-0301-z
关键词
Prostate cancer; PET/MR; Multiparametric analysis; Ga-68-PSMA; Tumor biology
Current imaging procedures for prostate cancer including positron emission tomography (PET) exhibit considerable limitations and are not always able to meet the diagnostic needs. Recently, a (68)Gallium-labeled ligand of the prostate-specific membrane antigen (Ga-68-PSMA) has been introduced in PET-imaging of prostate cancer with first promising results. Due to relatively exclusive expression of PSMA in prostatic tissue as well as increased expression in prostate cancer, 68 Ga-PSMA was reported to exhibit a favorable lesion to background ratio. Together with the novel development of combined PET/MRI, the combination of excellent morphological detail, multiparametric functional information, and molecular PET data might lead to a significant improvement in detection of prostate cancer. We present an exemplarily case of primary staging using multiparametric Ga-68-PSMA PET/MR by combining molecular and structural information.
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