3.8 Article Book Chapter

Chiral Phosphorus Ligands with Interesting Properties and Practical Applications

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SPRINGER-VERLAG BERLIN
DOI: 10.1007/978-3-642-19472-6_2

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Asymmetric hydrogenation; Bisphosphine ligands; Enantioselectively catalytic bond-formation; Mixed-donor ligands; Transition-metal catalysts

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Asymmetric transformations using a catalytic approach remain significantly important in organic synthesis, especially in the preparation of pharmaceutically interesting molecules. Indeed, chiral phosphorus ligands play an important role in this area. In this chapter, the recent development and advancement of chiral phosphines, phosphites, phosphoramides, etc. are reviewed. The potentially practical organic transformations are also described.

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