相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。The contribution of immune infiltrates and the local microenvironment in the pathogenesis of osteosarcoma
Marie-Francoise Heymann et al.
CELLULAR IMMUNOLOGY (2019)
TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α
Anahita Hamidi et al.
SCIENCE SIGNALING (2017)
TGF-β, Bone Morphogenetic Protein, and Activin Signaling and the Tumor Microenvironment
Michael W. Pickup et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Epithelial-to-mesenchymal transition, circulating tumor cells and cancer metastasis: Mechanisms and clinical applications
Xiao-Xiang Jie et al.
ONCOTARGET (2017)
TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α
Anahita Hamidi et al.
SCIENCE SIGNALING (2017)
CD163-positive tumor-associated macrophages and CD8-positive cytotoxic lymphocytes are powerful diagnostic markers for the therapeutic stratification of osteosarcoma patients: An immunohistochemical analysis of the biopsies fromthe French OS2006 phase 3 trial
Anne Gomez-Brouchet et al.
ONCOIMMUNOLOGY (2017)
TGF-β Signaling in Gastrointestinal Cancers: Progress in Basic and Clinical Research
Takehiko Yokobori et al.
JOURNAL OF CLINICAL MEDICINE (2017)
Stromal Modulators of TGF-β in Cancer
Brunella Costanza et al.
JOURNAL OF CLINICAL MEDICINE (2017)
Next-generation capillary electrophoresis-mass spectrometry approaches in metabolomics
Wei Zhang et al.
CURRENT OPINION IN BIOTECHNOLOGY (2017)
Dichotomous roles of TGF-β in human cancer
Jennifer J. Huang et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcoma
Pierre Kunz et al.
BMC CANCER (2016)
Zoledronate in combination with chemotherapy and surgery to treat osteosarcoma (OS2006): a randomised, multicentre, open-label, phase 3 trial
Sophie Piperno-Neumann et al.
LANCET ONCOLOGY (2016)
Agonists and Antagonists of TGF-β Family Ligands
Chenbei Chang
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Signaling Receptors for TGF-β Family Members
Carl-Henrik Heldin et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
TGF-β Signaling from Receptors to Smads
Akiko Hata et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins
Ian B. Robertson et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
Masato Morikawa et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2016)
Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma
Clotilde Dumars et al.
ONCOTARGET (2016)
TGF-β Signaling in Bone Remodeling and Osteosarcoma Progression
Audrey Lamora et al.
JOURNAL OF CLINICAL MEDICINE (2016)
TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease
Mengrui Wu et al.
BONE RESEARCH (2016)
Targeting the TGFβ pathway for cancer therapy
Cindy Neuzillet et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Structural determinants of Smad function in TGF-β signaling
Maria J. Macias et al.
TRENDS IN BIOCHEMICAL SCIENCES (2015)
Expression profile of Twist, vascular endothelial growth factor and CD34 in patients with different phases of osteosarcoma
Pengfei Lei et al.
ONCOLOGY LETTERS (2015)
Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation
Marianna Papaspyridonos et al.
NATURE COMMUNICATIONS (2015)
Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases
Audrey Lamora et al.
ONCOTARGET (2015)
CD8+/FOXP3+-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study
Benedikt Fritzsching et al.
ONCOIMMUNOLOGY (2015)
Cancer metastases: challenges and opportunities
Xiangming Guan
ACTA PHARMACEUTICA SINICA B (2015)
First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma
Jordi Rodon et al.
CLINICAL CANCER RESEARCH (2015)
TGFβ: A player on multiple fronts in the tumor microenvironment
Fabian Caja et al.
JOURNAL OF IMMUNOTOXICOLOGY (2015)
Overexpression of Smad7 Blocks Primary Tumor Growth and Lung Metastasis Development in Osteosarcoma
Audrey Lamora et al.
CLINICAL CANCER RESEARCH (2014)
Signaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition
Rik Derynck et al.
CURRENT OPINION IN CELL BIOLOGY (2014)
Transforming Growth Factor-Beta Polymorphisms and Serum Level in the Development of Osteosarcoma
Shaogang Xu et al.
DNA AND CELL BIOLOGY (2014)
Bisphosphonates Inhibit Osteosarcoma-Mediated Osteolysis Via Attenuation of Tumor Expression of MCP-1 and RANKL
Tetsuro Ohba et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2014)
TGF-β: Duality of Function Between Tumor Prevention and Carcinogenesis
Daniel R. Principe et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)
TWIST interacts with β-catenin signaling on osteosarcoma cell survival against cisplatin
Jianhuang Wu et al.
MOLECULAR CARCINOGENESIS (2014)
Molecular mechanisms of epithelial-mesenchymal transition
Samy Lamouille et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-ß signaling in U2OS cells
J. Y. Sung et al.
CELL DEATH & DISEASE (2014)
Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma
Xiang Chen et al.
CELL REPORTS (2014)
Translational biology of osteosarcoma
Maya Kansara et al.
NATURE REVIEWS CANCER (2014)
The relevance of the TGF-β Paradox to EMT-MET programs
Chevaun D. Morrison et al.
CANCER LETTERS (2013)
Targeting the PDGF signaling pathway in tumor treatment
Carl-Henrik Heldin
CELL COMMUNICATION AND SIGNALING (2013)
WHO Classification of Soft Tissue and Bone, fourth edition: summary and commentary
Andrew E. Rosenberg
CURRENT OPINION IN ONCOLOGY (2013)
Targeting TGF-β signaling in cancer
Lior H. Katz et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2013)
Benefits and Adverse Events in Younger Versus Older Patients Receiving Neoadjuvant Chemotherapy for Osteosarcoma: Findings From a Meta-Analysis
Marnie Collins et al.
JOURNAL OF CLINICAL ONCOLOGY (2013)
The up-regulation of cysteine-rich protein 61 induced by transforming growth factor beta enhances osteosarcoma cell migration
Jun Chen et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2013)
EMT transcription factors: implication in osteosarcoma
Guoqiong Yang et al.
MEDICAL ONCOLOGY (2013)
A systematic review of vascular endothelial growth factor expression as a biomarker of prognosis in patients with osteosarcoma
Ding Chen et al.
TUMOR BIOLOGY (2013)
Cancer stem cells in pediatric sarcomas
Filemon S. Dela Cruz
FRONTIERS IN ONCOLOGY (2013)
The roles of TGFβ in the tumour microenvironment
Michael Pickup et al.
NATURE REVIEWS CANCER (2013)
TGFβ signaling plays a critical role in promoting alternative macrophage activation
Dapeng Gong et al.
BMC IMMUNOLOGY (2012)
Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma
Aidong Shen et al.
JOURNAL OF SURGICAL ONCOLOGY (2012)
Podoplanin Is Regulated by AP-1 and Promotes Platelet Aggregation and Cell Migration in Osteosarcoma
Akiko Kunita et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Developmental and Pathological Angiogenesis
Alicia S. Chung et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
RLIM interacts with Smurf2 and promotes TGF-β induced U2OS cell migration
Yongsheng Huang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Addition of Pamidronate to Chemotherapy for the Treatment of Osteosarcoma
Paul A. Meyers et al.
CANCER (2011)
Genetic Amplification of the Vascular Endothelial Growth Factor (VEGF) Pathway Genes, Including VEGFA, in Human Osteosarcoma
Jilong Yang et al.
CANCER (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Tumor-Infiltrating Macrophages Are Associated with Metastasis Suppression in High-Grade Osteosarcoma: A Rationale for Treatment with Macrophage Activating Agents
Emilie P. Buddingh et al.
CLINICAL CANCER RESEARCH (2011)
Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands
Craig A. Harrison et al.
GROWTH FACTORS (2011)
Reciprocal Osteoblastic and Osteoclastic Modulation in Co-Cultured MG63 Osteosarcoma Cells and Human Osteoclast Precursors
Joao Costa-Rodrigues et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2011)
The Role of Tumor Stroma in Cancer Progression and Prognosis Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer
Roy M. Bremnes et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer
Sonia Tugues et al.
MOLECULAR ASPECTS OF MEDICINE (2011)
Latent TGF-β structure and activation
Minlong Shi et al.
NATURE (2011)
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
Peter Carmeliet et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Targeted therapy for high-grade glioma with the TGF-beta 2 inhibitor trabedersen: results of a randomized and controlled phase IIb study
U. Bogdahn et al.
NEURO-ONCOLOGY (2011)
Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity
Erica B. Wilson et al.
PLOS ONE (2011)
Stromal Endothelial Cells Directly Influence Cancer Progression
Joseph W. Franses et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Expression of Snail2 in long bone osteosarcomas correlates with tumour malignancy
Amir-Shaya Sharili et al.
TUMOR BIOLOGY (2011)
Macrophage Diversity Enhances Tumor Progression and Metastasis
Bin-Zhi Qian et al.
CELL (2010)
Cyclin-Dependent Kinase 4-Mediated Phosphorylation Inhibits Smad3 Activity in Cyclin D-Overexpressing Breast Cancer Cells
Stanislav Zelivianski et al.
MOLECULAR CANCER RESEARCH (2010)
Alternative lengthening of telomeres: models, mechanisms and implications
Anthony J. Cesare et al.
NATURE REVIEWS GENETICS (2010)
Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis
M. Petersen et al.
ONCOGENE (2010)
The polarization of immune cells in the tumour environment by TGFβ
Richard A. Flavell et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Transforming growth factor-beta signaling and tumor angiogenesis
Evangelia Pardali et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2009)
Inhibition of Transforming Growth Factor β Receptor I Kinase Blocks Hepatocellular Carcinoma Growth Through Neo-angiogenesis Regulation
Antonio Mazzocca et al.
HEPATOLOGY (2009)
Platelet-derived growth factor receptor as a prognostic marker and a therapeutic target for imatinib mesylate therapy in osteosarcoma
Tadahiko Kubo et al.
CANCER (2008)
TGF-β:: A master of all T cell trades
Ming O. Li et al.
CELL (2008)
Blockade of the RhoA-JNK-c-Jun-MMP2 Cascade by Atorvastatin Reduces Osteosarcoma Cell Invasion
Olivia Fromigue et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β
Motozo Yamashita et al.
MOLECULAR CELL (2008)
Zoledronic acid inhibits osteosarcoma growth in an orthotopic model
Crispin R. Dass et al.
MOLECULAR CANCER THERAPEUTICS (2007)
PDGF essentially links TGF-β signaling to nuclear β-catenin accumulation in hepatocellular carcinoma progression
A. N. M. Fischer et al.
ONCOGENE (2007)
Distinct role of macrophages in different tumor microenvironments
CE Lewis et al.
CANCER RESEARCH (2006)
Transforming growth factor-β signal transduction in angiogenesis and vascular disorders
P Bertolino et al.
CHEST (2005)
Transforming growth factor-β1 to the bone
K Janssens et al.
ENDOCRINE REVIEWS (2005)
Matrix metalloproteinases participate in osteosarcoma invasion
K Bjornland et al.
JOURNAL OF SURGICAL RESEARCH (2005)
Enhanced tumor regression and tissue repair when zoledronic acid is combined with ifosfamide in rat osteosarcoma
D Heymann et al.
BONE (2005)
TP53 mutations and outcome in osteosarcoma:: A prospective, multicenter study
JS Wunder et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells
S Maeda et al.
EMBO JOURNAL (2004)
GADD34-PP1c recruited by Smad7 dephosphorylates TGFβ type 1 receptor
WB Shi et al.
JOURNAL OF CELL BIOLOGY (2004)
RANKL/RANK/OPG:: new therapeutic targets in bone tumours and associated osteolysis
Y Wittrant et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2004)
Roles of stromal cell RANKL, OPG, and M-CSF expression in biphasic TGF-β regulation of osteoclast differentiation
M Karst et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2004)
Frequent amplification and rearrangement of chromosomal bands 6p12-p21 and 17p11.2 in osteosarcoma
CC Lau et al.
GENES CHROMOSOMES & CANCER (2004)
TGF β1 expression and angiogenesis in colorectal cancer tissue
B Xiong et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2002)
Immune-mediated eradication of tumors through the blockade of transforming growth factor-β signaling in T cells
L Gorelik et al.
NATURE MEDICINE (2001)
TGF-β-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation
T Alliston et al.
EMBO JOURNAL (2001)
Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
T Ebisawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Repression of p15INK4b expression by Myc through association with Miz-1
P Staller et al.
NATURE CELL BIOLOGY (2001)
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGFβ receptor for degradation
P Kavsak et al.
MOLECULAR CELL (2000)
Role of smad proteins and transcription factor Sp1 in p21Wafl/Cip1 regulation by transforming growth factor-β
K Pardali et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis
SP Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
分享论文
