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LANCET (2005)
ErbB2 overexpression in mammary cells upregulates VEGF through the core promoter
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The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
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CANCER RESEARCH (2004)
Association between HER-2/neu and vascular endothelial growth factor expression predicts clinical outcome in primary breast cancer patients
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CLINICAL CANCER RESEARCH (2004)
Incidence of cerebral metastases in patients treated with trastuzumab for metastatic breast cancer
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BRITISH JOURNAL OF CANCER (2004)
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
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CANCER CELL (2004)
Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma
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CANCER (2003)
Cyclin D1, EMS1 and 11q13 amplification in breast cancer
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BREAST CANCER RESEARCH AND TREATMENT (2003)
PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest
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NATURE MEDICINE (2002)
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
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JOURNAL OF CLINICAL ONCOLOGY (2002)
Specific protection against breast cancers by cyclin D1 ablation
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NATURE (2001)
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
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NEW ENGLAND JOURNAL OF MEDICINE (2001)
Angiogenesis in cancer and other diseases
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NATURE (2000)
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
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NATURE MEDICINE (2000)