相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Targeting nucleolin for better survival in diffuse large B-cell lymphoma
N. Jain et al.
LEUKEMIA (2018)
Application of aptamers in treatment and diagnosis of leukemia
Rezvan Yazdian-Robati et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)
Olaptesed pegol, an anti-CXCL12/SDF-1 Spiegelmer, alone and with bortezomib-dexamethasone in relapsed/refractory multiple myeloma: a Phase IIa Study
H. Ludwig et al.
LEUKEMIA (2017)
Monitoring immune-checkpoint blockade: response evaluation and biomarker development
Mizuki Nishino et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Oligonucleotide-based pharmaceuticals: Non-clinical and clinical safety signals and non-clinical testing strategies
Enni-Kaisa Mustonen et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2017)
A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis
Daniel Ajona et al.
CANCER DISCOVERY (2017)
Simultaneous targeting of CD44 and EpCAM with a bispecific aptamer effectively inhibits intraperitoneal ovarian cancer growth
Jingying Zheng et al.
THERANOSTICS (2017)
Increasing Tumor-Infiltrating T Cells through Inhibition of CXCL12 with NOX-A12 Synergizes with PD-1 Blockade
Dirk Zboralski et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Aptamer-based sandwich-type biosensors
Ho Bin Seo et al.
JOURNAL OF BIOLOGICAL ENGINEERING (2017)
A CTLA-4 Antagonizing DNA Aptamer with Antitumor Effect
Bo-Tsang Huang et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2017)
The Bioactivity of D-/L-Isonucleoside- and 2′-Deoxyinosine-Incorporated Aptamer AS1411s Including DNA Replication/MicroRNA Expression
Xinmeng Fan et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2017)
Therapeutic applications of synthetic nucleic acid aptamers
Suttinee Poolsup et al.
CURRENT OPINION IN BIOTECHNOLOGY (2017)
CXCL12 and CXCR7 are relevant targets to reverse cell adhesion-mediated drug resistance in multiple myeloma
Johannes M. Waldschmidt et al.
BRITISH JOURNAL OF HAEMATOLOGY (2017)
Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects
Sven Kruspe et al.
BIOMEDICINES (2017)
Development of Phosphorothioate DNA and DNA Thioaptamers
David E. Volk et al.
BIOMEDICINES (2017)
CXCL12/CXCR4: a symbiotic bridge linking cancer cells and their stromal neighbors in oncogenic communication networks
F. Guo et al.
ONCOGENE (2016)
Identification of TIM3 2′-fluoro oligonucleotide aptamer by HT-SELEX for cancer immunotherapy
Sandra Hervas-Stubbs et al.
ONCOTARGET (2016)
Aptamers in hematological malignancies and their potential therapeutic implications
Wanyan Ouyang et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2016)
Pre-existing anti-polyethylene glycol antibody linked to first-exposure allergic reactions to pegnivacogin, a PEGylated RNA aptamer
Nancy J. Ganson et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
An aptamer-antibody complex (oligobody) as a novel delivery platform for targeted cancer therapies
Kyun Heo et al.
JOURNAL OF CONTROLLED RELEASE (2016)
PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs
Peter L. Turecek et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
Next-generation polymer nanocomposite-based electrochemical sensors and biosensors: A review
Swati Shrivastava et al.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY (2016)
Fit for the Eye: Aptamers in Ocular Disorders
Daniel W. Drolet et al.
NUCLEIC ACID THERAPEUTICS (2016)
Targeting Two Coagulation Cascade Proteases with a Bivalent Aptamer Yields a Potent and Antidote-Controllable Anticoagulant
Erin E. Soule et al.
NUCLEIC ACID THERAPEUTICS (2016)
Aptamers: A promising chemical antibody for cancer therapy
Gang Zhou et al.
ONCOTARGET (2016)
MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells
Mario Martinez Soldevilla et al.
ONCOTARGET (2016)
E-selectin Targeting PEGylated-thioaptamer Prevents Breast Cancer Metastases
Yoshihiro Morita et al.
Molecular Therapy-Nucleic Acids (2016)
A Novel PD-L1-targeting Antagonistic DNA Aptamer With Antitumor Effects
Wei-Yun Lai et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2016)
Modified Nucleoside Triphosphates for In-vitro Selection Techniques
Maria A. Dellafiore et al.
FRONTIERS IN CHEMISTRY (2016)
Aptamers in Therapeutics
Abhishek Parashar
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (2016)
Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy
Lingegowda S. Mangala et al.
JCI INSIGHT (2016)
The roles of nucleolin subcellular localization in cancer
Caroline Madeleine Berger et al.
BIOCHIMIE (2015)
2-fluoro-RNA oligonucleotide CD40 targeted aptamers for the control of B lymphoma and bone-marrow aplasia
Mario Martinez Soldevilla et al.
BIOMATERIALS (2015)
Nucleic acid aptamers in cancer research, diagnosis and therapy
Haitao Ma et al.
CHEMICAL SOCIETY REVIEWS (2015)
Aptamers: Molecular Tools for Medical Diagnosis
Veli Cengiz Ozalp et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)
Postoperative hemicrania continua-like headache - a case series
Andreas R. Gantenbein et al.
JOURNAL OF HEADACHE AND PAIN (2015)
Blocking the Adhesion Cascade at the Premetastatic Niche for Prevention of Breast Cancer Metastasis
Shin-Ae Kang et al.
MOLECULAR THERAPY (2015)
The isolation of an RNA aptamer targeting to p53 protein with single amino acid mutation
Liang Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition
Hsin-Yung Yen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice
Shin-Ae Kang et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2015)
Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers
Aaron Prodeus et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2015)
Pharmacokinetics of a Cholesterol-conjugated Aptamer Against the Hepatitis C Virus (HCV) NS5B Protein
Chang Ho Lee et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2015)
Reducing toxicity of 4-1BB costimulation: targeting 4-1BB ligands to the tumor stroma with bi-specific aptamer conjugates
B. Schrand et al.
ONCOIMMUNOLOGY (2015)
4-1 BB agonists: multi-potent potentiators of tumor immunity
Todd Bartkowiak et al.
FRONTIERS IN ONCOLOGY (2015)
Nucleic Acid Aptamer-Mediated Drug Delivery for Targeted Cancer Therapy
Huijie Zhu et al.
CHEMMEDCHEM (2015)
Thioaptamer Conjugated Liposomes for Tumor Vasculature Targeting
Aman P. Mann et al.
Oncotarget (2015)
Selection of DNA aptamers against epidermal growth factor receptor with high affinity and specificity
Deng-Liang Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
Julia Hoellenriegel et al.
BLOOD (2014)
NOX-A12: mobilizing CLL away from home
Roberto Marasca et al.
BLOOD (2014)
A DNA aptamer with high affinity and specificity for molecular recognition and targeting therapy of gastric cancer
Hong-Yong Cao et al.
BMC CANCER (2014)
Molecular Pathways: HER3 Targeted Therapy
Kinisha Gala et al.
CLINICAL CANCER RESEARCH (2014)
A cell-based single-stranded DNA aptamer specifically targets gastric cancer
Xiaojiao Zhang et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma
Jonathan E. Rosenberg et al.
INVESTIGATIONAL NEW DRUGS (2014)
PD-1 identifies the patient-specific CD8+ tumor-reactive repertoire infiltrating human tumors
Alena Gros et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Bone marrow endothelium-targeted therapeutics for metastatic breast cancer
Junhua Mai et al.
JOURNAL OF CONTROLLED RELEASE (2014)
DNA aptamer raised against advanced glycation end products inhibits melanoma growth in nude mice
Ayako Ojima et al.
LABORATORY INVESTIGATION (2014)
Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane Antigen
Justin P. Dassie et al.
MOLECULAR THERAPY (2014)
Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats
Shie-Chau Liu et al.
NEURO-ONCOLOGY (2014)
Cell Surface Nucleolin as a Target for Anti-Cancer Therapies
Marina Koutsioumpa et al.
RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY (2014)
Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients
Michael S. Hershfield et al.
ARTHRITIS RESEARCH & THERAPY (2014)
DNA-Aptamer Targeting Vimentin for Tumor Therapy In Vivo
Tatyana N. Zamay et al.
NUCLEIC ACID THERAPEUTICS (2014)
Mechanism of Alternative Complement Pathway Dysregulation by a Phosphorothioate Oligonucleotide in Monkey and Human Serum
Scott P. Henry et al.
NUCLEIC ACID THERAPEUTICS (2014)
SDF-1 Inhibition Targets the Bone Marrow Niche for Cancer Therapy
Aldo M. Roccaro et al.
CELL REPORTS (2014)
Targeting 4-1BB Costimulation to the Tumor Stroma with Bispecific Aptamer Conjugates Enhances the Therapeutic Index of Tumor Immunotherapy
Brett Schrand et al.
CANCER IMMUNOLOGY RESEARCH (2014)
A Novel Investigational Fc-Modified Humanized Monoclonal Antibody, Motavizumab-YTE, Has an Extended Half-Life in Healthy Adults
Gabriel J. Robbie et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2013)
Proliferation and migration of tumor cells in tapered channels
Yuan Wan et al.
BIOMEDICAL MICRODEVICES (2013)
Hematopoietic Stem and Progenitor Cell Mobilization in Mice and Humans by a First-in-Class Mirror-Image Oligonucleotide Inhibitor of CXCL12
A. Vater et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Periostin-binding DNA Aptamer Inhibits Breast Cancer Growth and Metastasis
Yu Jin Lee et al.
MOLECULAR THERAPY (2013)
Investigating the Antiproliferative Activity of High Affinity DNA Aptamer on Cancer Cells
Harleen Kaur et al.
PLOS ONE (2013)
Potential Capacity of Aptamers to Trigger Immune Activation in Human Blood
Meltem Avci-Adali et al.
PLOS ONE (2013)
Targeting CXCL12 from FAP-expressing carcinomaassociated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer
Christine Feig et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth
Georg Mahlknecht et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Identification and Characterization of an Agonistic Aptamer Against the T Cell Costimulatory Receptor, OX40
Elizabeth D. Pratico et al.
NUCLEIC ACID THERAPEUTICS (2013)
CD28 Aptamers as Powerful Immune Response Modulators
Fernando Pastor et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
A Review of Therapeutic Aptamer Conjugates with Emphasis on New Approaches
John G. Bruno
PHARMACEUTICALS (2013)
Toggled RNA Aptamers Against Aminoglycosides Allowing Facile Detection of Antibiotics Using Gold Nanoparticle Assays
Nicola Derbyshire et al.
ANALYTICAL CHEMISTRY (2012)
Inhibitory RNA aptamer against SP6 RNA polymerase
Yusuke Mori et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Aptamer-Mediated Blockade of IL4Rα Triggers Apoptosis of MDSCs and Limits Tumor Progression
Felix Roth et al.
CANCER RESEARCH (2012)
Apolipoprotein B Synthesis Inhibition With Mipomersen in Heterozygous Familial Hypercholesterolemia
Evan A. Stein et al.
CIRCULATION (2012)
PEGylation of Proteins and Liposomes: a Powerful and Flexible Strategy to Improve the Drug Delivery
Paola Milla et al.
CURRENT DRUG METABOLISM (2012)
An RNA Aptamer That Binds Carcinoembryonic Antigen Inhibits Hepatic Metastasis of Colon Cancer Cells in Mice
Young Ju Lee et al.
GASTROENTEROLOGY (2012)
Toll-like receptor (TLR) 3 immune modulation by unformulated small interfering RNA or DNA and the role of CD14 (in TLR-mediated effects)
Cordula Weber et al.
IMMUNOLOGY (2012)
State of the art in PEGylation: The great versatility achieved after forty years of research
Gianfranco Pasut et al.
JOURNAL OF CONTROLLED RELEASE (2012)
A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity
K. M. Bompiani et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)
Isolation and Optimization of Murine IL-10 Receptor Blocking Oligonucleotide Aptamers Using High-throughput Sequencing
Alexey Berezhnoy et al.
MOLECULAR THERAPY (2012)
Targeting Axl With an High-affinity Inhibitory Aptamer
Laura Cerchia et al.
MOLECULAR THERAPY (2012)
Randomized, Placebo-Controlled Trial of Mipomersen in Patients with Severe Hypercholesterolemia Receiving Maximally Tolerated Lipid-Lowering Therapy
Mary P. McGowan et al.
PLOS ONE (2012)
Polyvalent nucleic acid aptamers and modulation of their activity: a focus on the thrombin binding aptamer
Domenica Musumeci et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Degradation of Nuclease-Stabilized RNA Oligonucleotides in Mycoplasma-Contaminated Cell Culture Media
Frank J. Hernandez et al.
NUCLEIC ACID THERAPEUTICS (2012)
E-Selectin-Targeted Porous Silicon Particle for Nanoparticle Delivery to the Bone Marrow
Aman P. Mann et al.
ADVANCED MATERIALS (2011)
Targeting 4-1BB Costimulation to Disseminated Tumor Lesions With Bi-specific Oligonucleotide Aptamers
Fernando Pastor et al.
MOLECULAR THERAPY (2011)
Inhibition of Cell Proliferation by an Anti-EGFR Aptamer
Na Li et al.
PLOS ONE (2011)
A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death
Carla Lucia Esposito et al.
PLOS ONE (2011)
Pharmacokinetic characterization of an RNA aptamer against osteopontin and demonstration of in vivo efficacy in reversing growth of human breast cancer cells
Lindsay Jones Talbot et al.
SURGERY (2011)
In Vitro Selection of RNA Aptamer and Specific Targeting of ErbB2 in Breast Cancer Cells
Mee Young Kim et al.
NUCLEIC ACID THERAPEUTICS (2011)
Coupling Aptamers to Short Interfering RNAs as Therapeutics
Laura Cerchia et al.
PHARMACEUTICALS (2011)
Discovery and Development of Therapeutic Aptamers
P. R. Bouchard et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
Engineering Dendritic Aptamer Assemblies as Superior Inhibitors of Protein Function
Youngmi Kim et al.
CHEMISTRY-AN ASIAN JOURNAL (2010)
Efficacy and Safety of Mipomersen, an Antisense Inhibitor of Apolipoprotein B, in Hypercholesterolemic Subjects Receiving Stable Statin Therapy
Fatima Akdim et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2010)
Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
Frederick J. Raal et al.
LANCET (2010)
Molecular Evolution of Functional Nucleic Acids with Chemical Modifications
Masayasu Kuwahara et al.
MOLECULES (2010)
The emerging field of RNA nanotechnology
Peixuan Guo
NATURE NANOTECHNOLOGY (2010)
Aptamers as therapeutics
Anthony D. Keefe et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Identification of Thioaptamer Ligand against E-Selectin: Potential Application for Inflamed Vasculature Targeting
Aman P. Mann et al.
PLOS ONE (2010)
Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer
Joseph Paul Eder et al.
CLINICAL CANCER RESEARCH (2009)
Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes
S. G. Sayyed et al.
DIABETOLOGIA (2009)
Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
Paula J. Bates et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2009)
Plasma Membrane Nucleolin Is a Receptor for the Anticancer Aptamer AS1411 in MV4-11 Leukemia Cells
Sridharan Soundararajan et al.
MOLECULAR PHARMACOLOGY (2009)
RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells
Zhiyong Mi et al.
MOLECULAR THERAPY (2009)
A Hybrid DNA Aptamer-Dendrimer Nanomaterial for Targeted Cell Labeling
Jing Zhou et al.
MACROMOLECULAR BIOSCIENCE (2009)
The nucleolin targeting aptamer AS1411 destabilizes bcl-2 messenger RNA in human breast cancer cells
Sridharan Soundararajan et al.
CANCER RESEARCH (2008)
Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer
Claudia M. Dollins et al.
CHEMISTRY & BIOLOGY (2008)
Multivalent 4-1BB binding aptamers costimulate CD8(+) T cells and inhibit tumor growth in mice
James O. McNamara et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin
Jing Mi et al.
MOLECULAR THERAPY (2008)
Local tolerance and systemic safety of pegaptanib sodium in the dog and rabbit
Jeffrey W. -D. Foy et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2007)
One-step selection of Vaccinia virus-binding DNA aptamers by MonoLEX
Andreas Nitsche et al.
BMC BIOTECHNOLOGY (2007)
ErbB receptors: from oncogenes to targeted cancer therapies
Hongtao Zhang et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Sequential loss of tumor vessel pericytes and endothelial cells after inhibition of platelet-derived growth factor B by selective aptamer AX102
Barbara Sennino et al.
CANCER RESEARCH (2007)
Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients
Jonathan K. Armstrong et al.
CANCER (2007)
LNA derivatives of a kissing aptamer targeted to the trans-activating responsive RNA element of HIV-1
Isabelle Lebars et al.
BLOOD CELLS MOLECULES AND DISEASES (2007)
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: Mechanism of activation and insights into differential inhibitor sensitivity
Cai-Hong Yun et al.
CANCER CELL (2007)
Combinatorial selection and delivery of thioaptamers
V. Thiviyanathan et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2007)
Reversible site-specific tagging of enzymatically synthesized RNAs using aldehyde-hydrazine chemistry and protease-cleavable linkers
Stephanie Pfander et al.
NUCLEIC ACIDS RESEARCH (2007)
Immunostimulatory monoclonal antibodies for cancer therapy
Ignacio Melero et al.
NATURE REVIEWS CANCER (2007)
Development of a sensitive and specific in situ hybridization technique for the cellular localization of antisense oligodeoxynucleotide drugs in tissue sections
Nancy Goebl et al.
TOXICOLOGIC PATHOLOGY (2007)
Discovery and development of anticancer aptamers
Christopher R. Ireson et al.
MOLECULAR CANCER THERAPEUTICS (2006)
AGRO100 inhibits activation of nuclear factor-κB (NF-κB) by forming a complex with NF-κB essential modulator (NEMO) and nucleolin
Allicia C. Girvan et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Intraocular injection of an aptamer that binds PDGF-B: A potential treatment for proliferative retinopathies
H Akiyama et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2006)
A phase I safety and dose escalation trial of docetaxel combined with GEM®231, a second generation antisense oligonucleotide targeting protein kinase A R1α in patients with advanced solid cancers
S Goel et al.
INVESTIGATIONAL NEW DRUGS (2006)
Multitasking by multivalent circular DNA aptamers
DA Di Giusto et al.
CHEMBIOCHEM (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
EWM Ng et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Therapeutic potential of Toll-like receptor 9 activation
Arthur M. Krieg
NATURE REVIEWS DRUG DISCOVERY (2006)
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
SQ Li et al.
CANCER CELL (2005)
Direct in vitro selection of a 2 '-O-methyl aptamer to VEGF
PE Burmeister et al.
CHEMISTRY & BIOLOGY (2005)
Pegaptanib - In exudative age-related macular degeneration
MAA Siddiqui et al.
DRUGS (2005)
In vivo activity of nuclease-resistant siRNAs
JM Layzer et al.
RNA (2004)
Antidote-mediated control of an anticoagulant aptamer in vivo
CP Rusconi et al.
NATURE BIOTECHNOLOGY (2004)
A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment
DA Daniels et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Neutralization of infectivity of diverse R5 clinical isolates of human immunodeficiency virus type 1 by gp120-binding 2′F-RNA aptamers
M Khati et al.
JOURNAL OF VIROLOGY (2003)
Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells
C Buerger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3
CHB Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2 '-O-(2-methoxyethyl) modified antisense oligonucleotide: Comparison across species
RS Geary et al.
DRUG METABOLISM AND DISPOSITION (2003)
A Y639F/H784A T7 RNA polymerase double mutant displays superior properties for synthesizing RNAs with non-canonical NTPs
R Padilla et al.
NUCLEIC ACIDS RESEARCH (2002)
Solution structure and design of dithiophosphate backbone aptamers targeting transcription factor NF-κB
DE Volk et al.
BIOORGANIC CHEMISTRY (2002)
Complement activation is responsible for acute toxicities in rhesus monkeys treated with a phosphorothioate oligodeoxynucleotide
SP Henry et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2002)
RNA aptamers as reversible antagonists of coagulation factor IXa
CP Rusconi et al.
NATURE (2002)
Tenascin-C aptamers are generated using tumor cells and purified protein
BJ Hicke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Untangling the ErbB signalling network
Y Yarden et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
DW Drolet et al.
PHARMACEUTICAL RESEARCH (2000)
Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood
H Dougan et al.
NUCLEAR MEDICINE AND BIOLOGY (2000)