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The regulation and function of YAP transcription co-activator
Chu Zhu et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2015)
Hippo-YAP signaling pathway: A new paradigm for cancer therapy
Yanlei Ma et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
The Hippo pathway in chemotherapeutic drug resistance
Yulei Zhao et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway
G. Liu et al.
ONCOGENE (2015)
Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression
Y-L Hsu et al.
ONCOGENE (2015)
TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells
M. Bartucci et al.
ONCOGENE (2015)
Personalized Oncogenomics: Clinical Experience with Malignant Peritoneal Mesothelioma Using Whole Genome Sequencing
Brandon S. Sheffield et al.
PLOS ONE (2015)
Prognostic Value of Yes-Associated Protein 1 (YAP1) in Various Cancers: A Meta-Analysis
Zhenqiang Sun et al.
PLOS ONE (2015)
Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma
Katherine K. Slemmons et al.
PLOS ONE (2015)
Mutant Gq/11 Promote Uveal Melanoma Tumorigenesis by Activating YAP
Fa-Xing Yu et al.
CANCER CELL (2014)
Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
Xiaodong Feng et al.
CANCER CELL (2014)
Yes-associated protein 1 (YAP1) promotes human gallbladder tumor growth via activation of the AXL/MAPK pathway
Maolan Li et al.
CANCER LETTERS (2014)
Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer
Masaki Mori et al.
CELL (2014)
Sensing the local environment: actin architecture and Hippo signalling
Pedro Gaspar et al.
CURRENT OPINION IN CELL BIOLOGY (2014)
Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis
Allison N. Lau et al.
EMBO JOURNAL (2014)
The extracellular matrix modulates the hallmarks of cancer
Michael W. Pickup et al.
EMBO REPORTS (2014)
The clinically used photosensitizer Verteporfin (VP) inhibits YAP-TEAD and human retinoblastoma cell growth in vitro without light activation
Katarzyna Brodowska et al.
EXPERIMENTAL EYE RESEARCH (2014)
YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth
Boon Chuan Low et al.
FEBS LETTERS (2014)
Activation of β-Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice
Junyan Tao et al.
GASTROENTEROLOGY (2014)
The Hippo Pathway Effectors TAZ/YAP Regulate Dicer Expression and MicroRNA Biogenesis through Let-7
Steven G. Chaulk et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
The Transcriptional Regulators TAZ and YAP Direct Transforming Growth Factor β-induced Tumorigenic Phenotypes in Breast Cancer Cells
Samantha E. Hiemer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transition
Maren Diepenbruck et al.
JOURNAL OF CELL SCIENCE (2014)
Pro-Invasive Activity of the Hippo Pathway Effectors YAP and TAZ in Cutaneous Melanoma
Flore Nallet-Staub et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
Identification, Mechanism of Action, and Antitumor Activity of a Small Molecule Inhibitor of Hippo, TGF-β, and Wnt Signaling Pathways
Dipanjan Basu et al.
MOLECULAR CANCER THERAPEUTICS (2014)
A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway
Morvarid Mohseni et al.
NATURE CELL BIOLOGY (2014)
Metabolic control of YAP and TAZ by the mevalonate pathway
Giovanni Sorrentino et al.
NATURE CELL BIOLOGY (2014)
THE BIOLOGY OF YAP/TAZ: HIPPO SIGNALING AND BEYOND
Stefano Piccolo et al.
PHYSIOLOGICAL REVIEWS (2014)
In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival
Moritz Menzel et al.
PIGMENT CELL & MELANOMA RESEARCH (2014)
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility
Zhongyuan Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration
Jonathan W. Haskins et al.
SCIENCE SIGNALING (2014)
Oncotargeting G proteins: The Hippo in the room
Xiaodong Feng et al.
ONCOTARGET (2014)
The Hippo Transducer TAZ Interacts with the SWI/SNF Complex to Regulate Breast Epithelial Lineage Commitment
Adam Skibinski et al.
CELL REPORTS (2014)
Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein
Michael DeRan et al.
CELL REPORTS (2014)
Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters
Alexandra Naba et al.
ELIFE (2014)
The Hippo pathway in disease and therapy: cancer and beyond
Marta Gomez et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2014)
Src Family Kinases as Novel Therapeutic Targets to Treat Breast Cancer Brain Metastases
Siyuan Zhang et al.
CANCER RESEARCH (2013)
BMP4 is a novel transcriptional target and mediator of mammary cell migration downstream of the Hippo pathway component TAZ
Dulcie Lai et al.
CELLULAR SIGNALLING (2013)
MicroRNA-200a Promotes Anoikis Resistance and Metastasis by Targeting YAP1 in Human Breast Cancer
San-Jian Yu et al.
CLINICAL CANCER RESEARCH (2013)
The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and development
Evan R. Barry et al.
CURRENT OPINION IN CELL BIOLOGY (2013)
MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis
Yi. Tang et al.
DEVELOPMENTAL CELL (2013)
Regulation of Hippo Signaling by EGFR-MAPK Signaling through Ajuba Family Proteins
B. V. V. G. Reddy et al.
DEVELOPMENTAL CELL (2013)
Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila
Masato Enomoto et al.
EMBO REPORTS (2013)
Bone metastatic process of breast cancer involves methylation state affecting E-cadherin expression through TAZ and WWOX nuclear effectors
Emanuela Matteucci et al.
EUROPEAN JOURNAL OF CANCER (2013)
Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation
Fa-Xing Yu et al.
GENES & DEVELOPMENT (2013)
The Hippo pathway: regulators and regulations
Fa-Xing Yu et al.
GENES & DEVELOPMENT (2013)
Novel YAP1-TFE3 fusion defines a distinct subset of epithelioid hemangioendothelioma
Cristina R. Antonescu et al.
GENES CHROMOSOMES & CANCER (2013)
HIF1α and HIF2α independently activate SRC to promote melanoma metastases
Sara C. Hanna et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
Fernando Calvo et al.
NATURE CELL BIOLOGY (2013)
YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14
J-M Huang et al.
ONCOGENE (2013)
TAZ Expression as a Prognostic Indicator in Colorectal Cancer
Hiu-Fung Yuen et al.
PLOS ONE (2013)
Regulation of Hippo pathway by mitogenic growth factors via phosphoinositide 3-kinase and phosphoinositide-dependent kinase-1
Run Fan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Integrins and metastasis
Kirat Kumar Ganguly et al.
CELL ADHESION & MIGRATION (2013)
Nuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancer
Eva J. Vlug et al.
CELLULAR ONCOLOGY (2013)
YAP Promotes Breast Cell Proliferation and Survival Partially through Stabilizing the KLF5 Transcription Factor
Xu Zhi et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Evaluation of Tumor Stiffness by Elastography Is Predictive for Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer
Mitsuhiro Hayashi et al.
ANNALS OF SURGICAL ONCOLOGY (2012)
MST1 mutations in autosomal recessive primary immunodeficiency characterized by defective naive T-cell survival
Nadine T. Nehme et al.
BLOOD (2012)
Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
Fa-Xing Yu et al.
CELL (2012)
β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
Joseph Rosenbluh et al.
CELL (2012)
Role of TAZ as Mediator of Wnt Signaling
Luca Azzolin et al.
CELL (2012)
TAZ induces growth factor-independent proliferation through activation of EGFR ligand amphiregulin
Nuo Yang et al.
CELL CYCLE (2012)
Yes-associated protein promotes tumour development in luminal epithelial derived breast cancer
Xiaodan Wang et al.
EUROPEAN JOURNAL OF CANCER (2012)
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
Jung-Soon Mo et al.
GENES & DEVELOPMENT (2012)
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
Yi Liu-Chittenden et al.
GENES & DEVELOPMENT (2012)
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
Bin Zhao et al.
GENES & DEVELOPMENT (2012)
Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data
Marieke L. Kuijjer et al.
GENES CHROMOSOMES & CANCER (2012)
YES-ASSOCIATED PROTEIN 1 PROMOTES ADENOCARCINOMA GROWTH AND METASTASIS THROUGH ACTIVATION OF THE RECEPTOR TYROSINE KINASE Axl
Z-L. Cui et al.
INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (2012)
The N-terminal Phosphodegron Targets TAZ/WWTR1 Protein for SCFβ-TrCP-dependent Degradation in Response to Phosphatidylinositol 3-Kinase Inhibition
Wei Huang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The extracellular matrix: A dynamic niche in cancer progression
Pengfei Lu et al.
JOURNAL OF CELL BIOLOGY (2012)
Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice
Miki Nishio et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth
Makiko Fujii et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
YAP mediates crosstalk between the Hippo and PI(3)K-TOR pathways by suppressing PTEN via miR-29
Karen Tumaneng et al.
NATURE CELL BIOLOGY (2012)
LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker
Dahu Chen et al.
NATURE MEDICINE (2012)
Transduction of mechanical and cytoskeletal cues by YAP and TAZ
Georg Halder et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
YAP induces malignant mesothelioma cell proliferation by upregulating transcription of cell cycle-promoting genes
T. Mizuno et al.
ONCOGENE (2012)
Inherited MST1 Deficiency Underlies Susceptibility to EV-HPV Infections
Amandine Crequer et al.
PLOS ONE (2012)
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
John M. Lamar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Regulation of the Hippo pathway by cell architecture and mechanical signals
Molly C. Schroeder et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)
Coordinating developmental signaling: novel roles for the Hippo pathway
Xaralabos Varelas et al.
TRENDS IN CELL BIOLOGY (2012)
Integrins as therapeutic targets
Simon L. Goodman et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
The Initial Hours of Metastasis: The Importance of Cooperative Host-Tumor Cell Interactions during Hematogenous Dissemination
Myriam Labelle et al.
CANCER DISCOVERY (2012)
Lysyl Oxidase, Extracellular Matrix Remodeling and Cancer Metastasis
Qian Xiao et al.
CANCER MICROENVIRONMENT (2012)
The Hippo pathway and apico-basal cell polarity
Alice Genevet et al.
BIOCHEMICAL JOURNAL (2011)
PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo
Jin-gui Ma et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells
Michelangelo Cordenonsi et al.
CELL (2011)
Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis
Wei Kang et al.
CLINICAL CANCER RESEARCH (2011)
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma
Krishna P. L. Bhat et al.
GENES & DEVELOPMENT (2011)
A Novel WWTR1-CAMTA1 Gene Fusion Is a Consistent Abnormality in Epithelioid Hemangioendothelioma of Different Anatomic Sites
Costantino Errani et al.
GENES CHROMOSOMES & CANCER (2011)
Connective Tissue Growth Factor Autocriny in Human Hepatocellular Carcinoma: Oncogenic Role and Regulation by Epidermal Growth Factor Receptor/Yes-Associated Protein-Mediated Activation
Raquel Urtasun et al.
HEPATOLOGY (2011)
A cell-based assay to screen stimulators of the Hippo pathway reveals the inhibitory effect of dobutamine on the YAP-dependent gene transcription
Yijun Bao et al.
JOURNAL OF BIOCHEMISTRY (2011)
The Human Adenocarcinoma-associated Gene, AGR2, Induces Expression of Amphiregulin through Hippo Pathway Co-activator YAP1 Activation
Aiwen Dong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways
Pei-Hsuan Chen et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2011)
Role of YAP/TAZ in mechanotransduction
Sirio Dupont et al.
NATURE (2011)
AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma
M. Z. Xu et al.
ONCOGENE (2011)
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene
X. Zhang et al.
ONCOGENE (2011)
Yes-Associated Protein Expression in Head and Neck Squamous Cell Carcinoma Nodal Metastasis
Lin Ge et al.
PLOS ONE (2011)
CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma
Hui Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Identification of a Disease-Defining Gene Fusion in Epithelioid Hemangioendothelioma
Munir R. Tanas et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Integrin Targeted Therapeutics
Melissa Millard et al.
THERANOSTICS (2011)
Identification of MET and SRC Activation in Melanoma Cell Lines Showing Primary Resistance to PLX4032
Elisabetta Vergani et al.
NEOPLASIA (2011)
Hippo Pathway Effector Yap Is an Ovarian Cancer Oncogene
Chad A. Hall et al.
CANCER RESEARCH (2010)
Advances in Targeting Src in the Treatment of Breast Cancer and Other Solid Malignancies
Erica L. Mayer et al.
CLINICAL CANCER RESEARCH (2010)
The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration
Phillip Karpowicz et al.
DEVELOPMENT (2010)
The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
Nailing Zhang et al.
DEVELOPMENTAL CELL (2010)
The Hippo Signaling Pathway in Development and Cancer
Duojia Pan
DEVELOPMENTAL CELL (2010)
The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
Jing Cai et al.
GENES & DEVELOPMENT (2010)
Structural insights into the YAP and TEAD complex
Ze Li et al.
GENES & DEVELOPMENT (2010)
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF beta-TRCP
Bin Zhao et al.
GENES & DEVELOPMENT (2010)
YAP1 and VGLL3, Encoding Two Cofactors of TEAD Transcription Factors, Are Amplified and Overexpressed in a Subset of Soft Tissue Sarcomas
Zofia Helias-Rodzewicz et al.
GENES CHROMOSOMES & CANCER (2010)
The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase
Chen-Ying Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Src Signaling in Cancer Invasion
Marcello Guarino
JOURNAL OF CELLULAR PHYSIOLOGY (2010)
Elevated c-Src and c-Yes expression in malignant skin cancers
Jang Hyun Lee et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2010)
Mutations in GNA11 in Uveal Melanoma.
Catherine D. Van Raamsdonk et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
Hai Song et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
Li Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Latent Bone Metastasis in Breast Cancer Tied to Src-Dependent Survival Signals
Xiang H. -F. Zhang et al.
CANCER CELL (2009)
α3β1 integrin promotes cell survival via multiple interactions between 14-3-3 isoforms and proapoptotic proteins
Ju-Eun Oh et al.
EXPERIMENTAL CELL RESEARCH (2009)
TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation
Siew Wee Chan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition
Heng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi
Catherine D. Van Raamsdonk et al.
NATURE (2009)
YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway
Jianmin Zhang et al.
NATURE CELL BIOLOGY (2009)
Src kinases as therapeutic targets for cancer
Lori C. Kim et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2009)
The expression of COX-2, hTERT, MDM2, LATS2 and S100A2 in different types of non-small cell lung cancer (NSCLC)
Mojca Strazisar et al.
CELLULAR & MOLECULAR BIOLOGY LETTERS (2009)
A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells
Siew Wee Chan et al.
CANCER RESEARCH (2008)
Negative regulation of YAP by LATS1 underscores evolutionary conservation of the Drosophila Hippo pathway
Jianmin Zhang et al.
CANCER RESEARCH (2008)
MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation
Maria Praskova et al.
CURRENT BIOLOGY (2008)
TEAD mediates YAP-dependent gene induction and growth control
Bin Zhao et al.
GENES & DEVELOPMENT (2008)
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
Qun-Ying Lei et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Src as a Therapeutic Target in Breast Cancer
Liam Morgan et al.
Endocrine Metabolic & Immune Disorders-Drug Targets (2008)
Tumor suppressor LATS1 is a negative regulator of oncogene YAP
Yawei Hao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
YAP1 increases organ size and expands undifferentiated progenitor cells
Fernando D. Camargo et al.
CURRENT BIOLOGY (2007)
Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma
Claudia Seidel et al.
MOLECULAR CARCINOGENESIS (2007)
Elucidation of a universal size-control mechanism in Drosophila and mammals
Jixin Dong et al.
CELL (2007)
A Src/Abl kinase inhibitor, SKI-606, blocks breast cancer invasion, growth, and metastasis in vitro and in vivo
Houda Jallal et al.
CANCER RESEARCH (2007)
G-protein-coupled receptors and cancer
Robert T. Dorsam et al.
NATURE REVIEWS CANCER (2007)
Multifaceted roles of Integrins in breast cancer metastasis
Donald E. White et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2007)
The Src signaling pathway: a potential target in melanoma and other malignancies
Jade Homsi et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
Promoter hypermethylation-mediated down-regulation of LATS 1 and LATS2 in human astrocytoma
Zheng Jiang et al.
NEUROSCIENCE RESEARCH (2006)
Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain
Asokan Anbanandam et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Integrin-regulated FAK-Src signaling in normal and cancer cells
Satyajit K. Mitra et al.
CURRENT OPINION IN CELL BIOLOGY (2006)
Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation
Bernard A. Callus et al.
FEBS JOURNAL (2006)
Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon
Michael Overholtzer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Role of c-Src in human MCF7 breast cancer cell tumorigenesis
Lorena Gonzalez et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Inhibition of protein kinase c-src reduces the incidence of breast cancer metastases and increases survival in mice: Implications for therapy
Nadia Rucci et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach
Lars Zender et al.
CELL (2006)
The human tumour suppressor LATS1 is activated by human MOB1 at the membrane
Alexander Hergovich et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Chromosome 6 deletion and candidate tumor suppressor genes in adenoid cystic carcinoma
Sue Rutherford et al.
CANCER LETTERS (2006)
Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor-positive breast cancer
MD Planas-Silva et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Multiple microalterations detected at high frequency in oral cancer
C Baldwin et al.
CANCER RESEARCH (2005)
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila homolog of YAP
JB Huang et al.
CELL (2005)
Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma
AM Snijders et al.
ONCOGENE (2005)
Array-based comparative genomic hybridization identifies localized DNA amplifications and homozygous deletions in pancreatic cancer
MD Bashyam et al.
NEOPLASIA (2005)
Integrin signaling in malignant melanoma
S Kuphal et al.
CANCER AND METASTASIS REVIEWS (2005)
Control of cell proliferation and apoptosis by Mob as tumor suppressor, Mats
ZC Lai et al.
CELL (2005)
Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers
Y Takahashi et al.
CLINICAL CANCER RESEARCH (2005)
Analysis of ovarian cancer cell lines using array-based comparative genomic hybridization
MBK Lambros et al.
JOURNAL OF PATHOLOGY (2005)
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
SK Zaidi et al.
EMBO JOURNAL (2004)
The emergence of integrins: a personal and historical perspective
RO Hynes
MATRIX BIOLOGY (2004)
The interplay between Src and integrins in normal and tumor biology
MP Playford et al.
ONCOGENE (2004)
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
JH Jia et al.
GENES & DEVELOPMENT (2003)
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway
RS Udan et al.
NATURE CELL BIOLOGY (2003)
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
S Pantalacci et al.
NATURE CELL BIOLOGY (2003)
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis
KF Harvey et al.
CELL (2003)
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
S Wu et al.
CELL (2003)
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes
ZY Dai et al.
HUMAN MOLECULAR GENETICS (2003)
Src family kinases in tumor progression and metastasis
JM Summy et al.
CANCER AND METASTASIS REVIEWS (2003)
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila
M Kango-Singh et al.
DEVELOPMENT (2002)
Allelic imbalance in selected chromosomal regions in ovarian cancer
LL Hansen et al.
CANCER GENETICS AND CYTOGENETICS (2002)
Integrins: Bidirectional, allosteric signaling machines
RO Hynes
CELL (2002)
Seven-transmembrane receptors
KL Pierce et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
salvador promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines
N Tapon et al.
CELL (2002)
TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
F Kanai et al.
EMBO JOURNAL (2000)
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