期刊
JOURNAL OF TISSUE ENGINEERING
卷 9, 期 -, 页码 -出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/2041731418768285
关键词
Hydrogels; biophysical parameters; stiffness; tissue regeneration; cell fate
资金
- National Research Foundation of Republic of Korea [NRF-2018R1A2B3003446]
- National Research Foundation of Korea [2018R1A2B3003446] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Hydrogels are three-dimensional polymeric networks filled with water and mimic tissue environments. Therefore, they are considered optimal to deliver cells and engineer damaged tissues. The hydrogel networks have been significantly modified to endow biochemical functionality with adhesive ligands, growth factors, or degradable sites that are helpful to drive proper cell functions. Recently, some of the biophysical properties of hydrogels have emerged as key players in dictating cell fate. Beyond static stiffness, time-dependent stress/strain changes in the interaction with cells and the cell-mediated degradation and matrix synthesis have been demonstrated to shape cell status and tissue repair process. We highlight here the emerging biophysical properties of hydrogels that can motivate tissue engineers to design and develop hydrogels optimally for tissue regeneration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据