期刊
WORLD JOURNAL OF CLINICAL ONCOLOGY
卷 2, 期 10, 页码 348-354出版社
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.5306/wjco.v2.i10.348
关键词
Parathyroid carcinoma; Positron emission tomography/computed tomography; 18F-Fluorodeoxyglucose; Restaging; Staging
类别
Parathyroid cancer is an uncommon malignant cancer and is associated with a poor prognosis. The staging of parathyroid cancer represents an important issue both at initial diagnosis and after surgery and medical treatment. The role of positron emission tomography/computed tomography (PET/CT) with 18F-Fluorodeoxyglucose (18F-FDG) as an imaging tool in parathyroid cancer is not clearly reported in the literature, although its impact in other cancers is well-defined. The aim of the following illustrative clinical cases is to highlight the impact of PET/CT in the management of different phases of parathyroid cancer. We describe five patients with parathyroid malignant lesions, who underwent FDG PET/CT at initial staging, restaging and post-surgery evaluation. In each patient we report the value of PET/CT comparing its findings with other common imaging modalities (e.g., CT, planar scintigraphy with 99mTc-sestamibi, magnetic resonance imaging) thus determining the complementary benefit of FDG PET/CT in parathyroid carcinoma. We hope to provide an insight into the potential role of PET/CT in assessing the extent of disease and response to treatment which are the general principles used to correctly evaluate disease status. (c) 2011 Baishideng. All rights reserved.
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