期刊
NATURE MICROBIOLOGY
卷 3, 期 3, 页码 261-262出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41564-018-0115-9
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CRISPR immunity begins with the acquisition of sequences from invading nucleic acids through spacer integration into a CRISPR locus. Off-target integration of spacers into other parts of the genome is now implicated as a spontaneous source of new CRISPR loci.
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