期刊
CARDIOVASCULAR ENGINEERING AND TECHNOLOGY
卷 9, 期 3, 页码 289-299出版社
SPRINGER
DOI: 10.1007/s13239-018-0349-y
关键词
Computational fluid dynamics; Fluid-structure interaction; Prosthetic heart valves; Thrombus assessment
资金
- NHLBI NIH HHS [R01 HL104080] Funding Source: Medline
The governing international standard for the development of prosthetic heart valves is International Organization for Standardization (ISO) 5840. This standard requires the assessment of the thrombus potential of transcatheter heart valve substitutes using an integrated thrombus evaluation. Besides experimental flow field assessment and ex vivo flow testing, computational fluid dynamics is a critical component of this integrated approach. This position paper is intended to provide and discuss best practices for the setup of a computational model, numerical solving, post-processing, data evaluation and reporting, as it relates to transcatheter heart valve substitutes. This paper is not intended to be a review of current computational technology; instead, it represents the position of the ISO working group consisting of experts from academia and industry with regards to considerations for computational fluid dynamic assessment of transcatheter heart valve substitutes.
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