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Multiplexing technology for in vitro diagnosis of pathogens: the key contribution of phosphorus dendrimers

期刊

SCIENCE CHINA-MATERIALS
卷 61, 期 11, 页码 1454-1461

出版社

SCIENCE PRESS
DOI: 10.1007/s40843-018-9253-5

关键词

phosphorus; dendrimers; diagnosis; DNA arrays; multiplexing technology

资金

  1. National Research Agency (Agence Nationale pour la Recherche), BIO-TECHNOLOGIES program [ANR 2010 BIOT 004 06]
  2. Region Midi Pyrenees [06001324, 07006292]
  3. CNRS

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After the microbiology based on Pasteur's method and polymerase chain reaction (PCR), the diagnosis company named Dendris has proposed a third-generation of diagnosis enabling the search of a broad range of pathogens with strong sensitivity and specificity. This extraordinary profile was possible thanks to the use of phosphorus dendrimers for which various techniques of deposition on a given support were investigated and described and analyzed in this report.

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