期刊
JOURNAL OF ADOLESCENT AND YOUNG ADULT ONCOLOGY
卷 7, 期 1, 页码 79-87出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/jayao.2017.0043
关键词
cognitive function; neuropsychological function; occupational function; employment; survivorship
类别
资金
- National Institute of Health, National Institute of Nursing Research, Cognitive Function and Work Productivity in Survivors of Adolescent Cancer [F31 NR014958]
- American Cancer Society, Doctoral Scholarship in Cancer Nursing, Cognitive and Work Function in Adult Survivors of Adolescent Cancer [DSCN-14-079-01-SCN]
- University of Pittsburgh, School of Nursing, Margaret E. Wilkes Scholarship Fund, Cognitive and Work Function in Adult Survivors of Adolescent Cancer
Purpose: Adolescents wih cancer have unique developmental considerations. These include brain development, particularly in the frontal lobe, and a focus on completing education and entering the workforce. Cancer and treatment at this stage may prove to uniquely affect survivors' experience of cognitive and occupational function. Methods: An exploratory, cross-sectional, descriptive comparative study was employed to describe cognitive and occupational function in adult survivors of adolescent cancer (diagnosed between the ages of 15 and 21 years) and explore differences in age- and gender-matched controls. Results: In total, 23 survivors and 14 controls participated in the study. While significant differences were not found between the groups on measures of cognitive and occupational function, several small and medium effect sizes were found suggesting that survivors may have greater difficulty than controls. Two small effect sizes were found in measures of neuropsychological performance (the Digit Vigilance test [d = 0.396] and Stroop test [d = 0.226]). Small and medium effect sizes ranging from 0.269 to 0.605 were found for aspects of perceived and total cognitive function. A small effect size was also found in work output (d = 0.367). Conclusions: While we did not find significant differences in cognitive or occupational function between survivors and controls, the effect sizes observed point to the need for future research. Future work using a larger sample size and longitudinal design are needed to further explore cognitive and occupational function in this vulnerable and understudied population and assist in the understanding of patterns of change over time.
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