期刊
FUNGAL BIOLOGY REVIEWS
卷 32, 期 3, 页码 118-130出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.fbr.2018.05.002
关键词
Aphanomyces invadans; Aquaculture; EGA; EUS; Oomycete
类别
资金
- University of Aberdeen
- BBSRC [BB/M026566/1, BB/P020224/1, BB/N005058/1, BB/J018333/1]
- NERC [NE/P010873/1]
- Ministry of Education Malaysia
Aphanomyces invadans is a eukaryotic pathogen and the causative agent of Epizootic Ulcerative Syndrome (EUS) in fish and is responsible for mortalities of up to 100% in aquaculture. A. invadans was first discovered in Japan in 1971, and since then it has been found in Australia, North America, Southern African countries and Asia. Methods for the correct identification of A. invadans are well established now and involve PCR-based detection and microscopy. However, the pathogenesis of A. invadans is poorly understood. Environmental stress (mainly temperature) and the associated immunocompromised fish seem to induce infections of A. invadans and outbreaks of EUS. Understanding the process of infection in more depth is fundamental for the discovery of novel effective treatments to combat the disease. In this review, we discuss morphological characteristics of A. invadans and its pathogenicity as well as various approaches of treatment. (C) 2018 British Mycological Society. Published by Elsevier Ltd. All rights reserved.
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