期刊
ARKIVOC
卷 -, 期 -, 页码 276-+出版社
ARKAT USA INC
DOI: 10.3998/ark.5550190.0012.a23
关键词
Ceric ammonium nitrate (CAN); indeno[1,2-b]pyridines; room temperature; 2,3,4,5,6-pentasubstituted pyridines
资金
- University Grants Commission, New Delhi
- UGC [37-398 / 2009 (SR)]
Ceric ammonium nitrate (CAN) (10 mol%) in ethanol has been found to be an efficient catalyst for the one-pot multi-component synthesis of fully substituted new indeno[1,2-b]pyridines through a combination of 1,3-indandione, propiophenone or 2-phenylacetophenone, aromatic aldehydes, and ammonium acetate at room temperature. The same methodology also worked well for the construction of several other 2,3,4,5,6-pentasubstituted pyridines at room temperature. Atom economy, excellent yields and mild reaction conditions are some of the important features of this protocol.
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