期刊
KOREAN CIRCULATION JOURNAL
卷 48, 期 7, 页码 565-590出版社
KOREAN SOC CARDIOLOGY
DOI: 10.4070/kcj.2018.0189
关键词
Heart transplantation; History; Current practice; Forecasting; Heart failure
资金
- Korean Society of Cardiology [201703-03]
- Basic Science Research Program through the National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [NRF-2018R1C1B6005448]
- Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI) - Ministry of Health & Welfare, Republic of Korea [HI18C0575]
Heart transplantation (HTx) has become standard treatment for selected patients with end-stage heart failure. Improvements in immunosuppressant, donor procurement, surgical techniques, and post-HTx care have resulted in a substantial decrease in acute allograft rejection, which had previously significantly limited survival of HTx recipients. However, limitations to long-term allograft survival exist, including rejection, infection, coronary allograft vasculopathy, and malignancy. Careful balance of immunosuppressive therapy and vigilant surveillance for complications can further improve long-term outcomes of HTx recipients.
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