相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Storage stability study of porcine hepatic and intestinal cytochrome P450 isoenzymes by use of a newly developed and fully validated highly sensitive HPLC-MS/MS method
Wim Schelstraete et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2018)
In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Gottingen Minipigs
Els Van Peer et al.
PHARMACEUTICAL RESEARCH (2017)
Constitutive expression and activity of cytochrome P450 in conventional pigs
Soren Drud Nielsen et al.
RESEARCH IN VETERINARY SCIENCE (2017)
Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes
Brahim Achour et al.
DRUG METABOLISM AND DISPOSITION (2017)
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing
Elke Gasthuys et al.
CURRENT PHARMACEUTICAL DESIGN (2016)
Specific features of pharmacokinetics in children
Petra Matalova et al.
DRUG METABOLISM REVIEWS (2016)
Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development
Natalie C. Sadler et al.
DRUG METABOLISM AND DISPOSITION (2016)
Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation
Robin E. Pearce et al.
DRUG METABOLISM AND DISPOSITION (2016)
The effect of the MC4R gene on boar taint compounds, sexual maturity and behaviour in growing-finishing boars and gilts
A. Van den Broeke et al.
ANIMAL (2015)
Age-related Differences in CYP3A Abundance and Activity in the Liver of the Gottingen Minipig
Els Van Peer et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2015)
Content and activity of human liver microsomal protein and prediction of individual hepatic clearance in vivo
Haifeng Zhang et al.
SCIENTIFIC REPORTS (2015)
Impact of age on hepatic cytochrome P450 of domestic male Camborough-29 pigs
S. X. Hu
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS (2015)
Microsomal protein per gram of liver (MPPGL) in paediatric biliary atresia patients
Lies De Bock et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2014)
Absolute protein quantification of clinically relevant cytochrome P450 enzymes and UDP-glucuronosyltransferases by mass spectrometry-based targeted proteomics
C. Groeer et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2014)
iTRAQ as a method for optimization: Enhancing peptide recovery after gel fractionation
Pieter Glibert et al.
PROTEOMICS (2014)
Differences in Cytochrome P450-Mediated Pharmacokinetics Between Chinese and Caucasian Populations Predicted by Mechanistic Physiologically Based Pharmacokinetic Modelling
Zoe E. Barter et al.
CLINICAL PHARMACOKINETICS (2013)
Xenobiotic Metabolizing Cytochrome P450 in Pig, a Promising Animal Model
Emanuela Puccinelli et al.
CURRENT DRUG METABOLISM (2013)
Animal models of toxicology testing: the role of pigs
Kristi L. Helke et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2013)
The mycotoxin T-2 inhibits hepatic cytochrome P4503A activity in pigs
J. Goossens et al.
FOOD AND CHEMICAL TOXICOLOGY (2013)
Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity
Lies De Bock et al.
TALANTA (2012)
Swine as Models in Biomedical Research and Toxicology Testing
M. M. Swindle et al.
VETERINARY PATHOLOGY (2012)
Cytochrome P450 Pig Liver Pie: Determination of Individual Cytochrome P450 Isoform Contents in Microsomes from Two Pig Livers Using Liquid Chromatography in Conjunction with Mass Spectroscopy
Brahim Achour et al.
DRUG METABOLISM AND DISPOSITION (2011)
Role of the cytochrome P450 enzyme system in veterinary pharmacokinetics: where are we now? Where are we going?
Leposava Antonovic et al.
FUTURE MEDICINAL CHEMISTRY (2011)
Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection
Hirotaka Kawakami et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2011)
Gender-related Differences in Cytochrome P450 in Porcine Liver - Implication for Activity, Expression and Inhibition by Testicular Steroids
M. K. Rasmussen et al.
REPRODUCTION IN DOMESTIC ANIMALS (2011)
Chlorzoxazone Metabolism by Porcine Cytochrome P450 Enzymes and the Effect of Cytochrome b5
P. Wiercinska et al.
DRUG METABOLISM AND DISPOSITION (2010)
The utility of the minipig as an animal model in regulatory toxicology
Gerd Bode et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2010)
Measurement of cytochrome P450 and NADPH-cytochrome P450 reductase
F. Peter Guengerich et al.
NATURE PROTOCOLS (2009)
Analyses of CYP2C in Porcine Microsomes
Mette T. Skaanild et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2008)
Covariation of Human Microsomal Protein Per Gram of Liver with Age: Absence of Influence of Operator and Sample Storage May Justify Interlaboratory Data Pooling
Z. E. Barter et al.
DRUG METABOLISM AND DISPOSITION (2008)
Midazolam metabolism in cytochrome P450 3A knockout mice can be attributed to up-regulated CYP2C enzymes
Robert A. B. van Waterschoot et al.
MOLECULAR PHARMACOLOGY (2008)
Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data:: Reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver
Zoe E. Barter et al.
CURRENT DRUG METABOLISM (2007)
Determination of a human hepatic microsomal scaling factor for predicting in vivo drug clearance
N Hakooz et al.
PHARMACEUTICAL RESEARCH (2006)
Porcine cytochrome P450 and metabolism
Mette Tingleff Skaanild
CURRENT PHARMACEUTICAL DESIGN (2006)
Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children
Trevor N. Johnson et al.
CLINICAL PHARMACOKINETICS (2006)
A mechanistic approach for the scaling of clearance in children
Andrea N. Edginton et al.
CLINICAL PHARMACOKINETICS (2006)
Prediction of drug disposition in infants and children by means of physiologically based pharmacokinetic (PBPK) modelling:: theophylline and midazolam as model drugs
S Björkman
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2005)
Inter-individual variability in levels of human microsomal protein and hepatocellularity per gram of liver
ZE Wilson et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2003)
The impact of cytochrome P450 2E1-dependent metabolic variance on a risk-relevant pharmacokinetic outcome in humans
JC Lipscomb et al.
RISK ANALYSIS (2003)
Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions
R Yuan et al.
DRUG METABOLISM AND DISPOSITION (2002)
Ontogeny of hepatic and renal systemic clearance pathways in infants - Part I
J Alcorn et al.
CLINICAL PHARMACOKINETICS (2002)
分享论文
