4.7 Article

A Novel Catecholopyrimidine Based Small Molecule PDE4B Inhibitor Suppresses Inflammatory Cytokines in Atopic Mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Medicinal

Design, synthesis, and biological evaluation of novel catecholopyrimidine based PDE4 inhibitor for the treatment of atopic dermatitis

Baskaran Purushothaman et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Dermatology

Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults

Eric L. Simpson et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2016)

Review Immunology

The cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory Diseases

Verena Katharina Raker et al.

FRONTIERS IN IMMUNOLOGY (2016)

Review Genetics & Heredity

The genomic landscape of human immune-mediated diseases

Xin Wu et al.

JOURNAL OF HUMAN GENETICS (2015)

Article Multidisciplinary Sciences

The Unrecognized Effects of Phosphodiesterase 4 on Epithelial Cells in Pulmonary Inflammation

Franziska M. Konrad et al.

PLOS ONE (2015)

Article Multidisciplinary Sciences

IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

Andrea Chiricozzi et al.

PLOS ONE (2014)

Review Cell Biology

Cyclic AMP-mediated immune regulation - Overview of mechanisms of action in T cells

Randi Mosenden et al.

CELLULAR SIGNALLING (2011)

Review Immunology

Atopic dermatitis: a disease of altered skin barrier and immune dysregulation

Mark Boguniewicz et al.

IMMUNOLOGICAL REVIEWS (2011)

Article Dermatology

Investigation of cytokine levels and their association with SCORAD index in adults with acute atopic dermatitis

E. Vakirlis et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2011)

Article Allergy

Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

Joseph A. Odhiambo et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2009)

Article Multidisciplinary Sciences

Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophages

Angie L. Hertz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Editorial Material Dermatology

A Role for Th17 Cells in the Immunopathogenesis of Atopic Dermatitis?

Antonella Di Cesare et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2008)

Article Clinical Neurology

Selective induction of cAMP phosphodiesterase PDE4132 expression in experimental autoimmune encephalomyelitis

Ellsabet Reyes-Irisarri et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)

Article Critical Care Medicine

Effect of 1-year treatment with roflumilast in severe chronic obstructive pulmonary disease

Peter M. A. Calverley et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2007)

Article Immunology

Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors

CL Weller et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2005)

Article Biochemistry & Molecular Biology

Anti-inflammatory potential of CB1-mediated cAMP elevation in mast cells

AL Small-Howard et al.

BIOCHEMICAL JOURNAL (2005)

Review Immunology

The regulation of immunoglobulin E class-switch recombination

RS Geha et al.

NATURE REVIEWS IMMUNOLOGY (2003)

Article Dermatology

Overexpression of IL-4 alters the homeostasis in the skin

A Elbe-Bürger et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2002)