期刊
CRITICAL CARE
卷 16, 期 3, 页码 -出版社
BIOMED CENTRAL LTD
DOI: 10.1186/cc11202
关键词
-
资金
- Innovative Medicines Initiative
- European Union [115153]
- European Federation of Pharmaceutical Industries and Associations [115153]
Among critically ill patients, the diagnosis of bloodstream infection poses a major challenge. Current standard bacterial identification based on blood culture platforms is intrinsically time-consuming and slow. The continuous evolvement of molecular techniques has the potential of providing a faster, more sensitive and direct identification of causative pathogens without prior need for cultivation. This may ultimately impact clinical decision-making and antimicrobial treatment. This review summarises the currently available technologies, their strengths and limitations and the obstacles that have to be overcome in order to develop a satisfactory bedside point-of-care diagnostic tool for detection of bloodstream infection.
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