期刊
PLANT SIGNALING & BEHAVIOR
卷 7, 期 2, 页码 217-221出版社
TAYLOR & FRANCIS INC
DOI: 10.4161/psb.18885
关键词
bacterial type III effector; chromatin; nucleus; plant immunity; transcription factor
资金
- French Agence National de la Recherche (ANR) [JC08_ 324792]
- Laboratoire d'Excellence (LABEX) [ANR-10-LABX-41]
In order to promote virulence, Gram-negative bacteria have evolved the ability to inject so-called type III effector proteins into host cells. The plant cell nucleus appears to be a subcellular compartment repeatedly targeted by bacterial effectors. In agreement with this observation, mounting evidence suggests that manipulation of host transcription is a major strategy developed by bacteria to counteract plant defense responses. It has been suggested that bacterial effectors may adopt at least three alternative, although not mutually exclusive, strategies to subvert host transcription. T3Es may (1) act as transcription factors that directly activate transcription in host cells, (2) affect histone packing and chromatin configuration, and/or (3) directly target host transcription factor activity. Here, we provide an overview on how all these strategies may lead to host transcriptional re-programming and, as a result, to improved bacterial multiplication inside plant cells.
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