期刊
INTERNATIONAL JOURNAL OF HEPATOLOGY
卷 2012, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2012/158547
关键词
-
资金
- National Institutes of Health [GM41804, AA15055, DK72237, AI077780]
- American Liver Foundation
- NIH [RO1 DK090962-01, RO1 DK072237-06, RO1 GM041804-24, P50 AA011999-13]
Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets.
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