期刊
MEDICAL MYCOLOGY CASE REPORTS
卷 1, 期 1, 页码 5-8出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.mmcr.2012.02.003
关键词
Esophageal candidiasis; Chronic mucocutaneous candidiasis; Esophageal cancer
Chronic esophageal candidiasis is an infection that is mostly seen in immunocompromised conditions, among which is chronic mucocutaneous candidiasis (CMC). Recently an association between CMC and esophageal carcinoma has been reported. Here we present two patients with chronic esophageal candidiasis who developed esophageal squamous cell carcinoma and we discuss the etiologic role of Candida-induced nitrosamine production, the loss of STAT1 function and impaired tumor surveillance and T-lymphocyte function in the development of esophageal carcinoma. (C) 2012 International Society for Human and Animal Mycology. Published by Elsevier B.V.
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