期刊
JOURNAL OF NANOTECHNOLOGY
卷 2012, 期 -, 页码 -出版社
HINDAWI LTD
DOI: 10.1155/2012/928924
关键词
-
资金
- Summer Faculty Fellowship from Missouri State University
- Cottrell College Science Award from Research Corporation for Science Advancement
- American Chemical Society Petroleum Research Fund [47532-GB10]
We investigated the antibacterial activity of single-walled carbon nanotubes (SWCNTs) dispersed in surfactant solutions of sodium cholate, sodium dodecylbenzene sulfonate, and sodium dodecyl sulfate. Among the three surfactants, sodium cholate demonstrated the weakest antibacterial activity against Salmonella enterica, Escherichia coli, and Enterococcus faecium and thereby was used to disperse bundled SWCNTs in order to study nanotube antibiotic activity. SWCNTs exhibited antibacterial characteristics for both S. enterica and E. coli. With the increase of nanotube concentrations from 0.3 mg/mL to 1.5 mg/mL, the growth curves had plateaus at lower absorbance values whereas the absorbance value was not obviously affected by the incubation ranging from 5min to 2 h. Our findings indicate that carbon nanotubes could become an effective alternative to antibiotics in dealing with drug- resistant and multidrug-resistant bacterial strains because of the physical mode of bactericidal action that SWCNTs display.
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