期刊
JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH
卷 42, 期 4, 页码 314-316出版社
ROYAL COLL PHYSICIANS EDINBURGH
DOI: 10.4997/JRCPE.2012.407
关键词
Opioids; adaptive servo-ventilation; central sleep apnoea
Sleep apnoea is a global health problem with significant morbidity. Obesity is a well-known risk factor for this condition, however chronic intake of opioids as a risk factor for central sleep apnoea is under-recognised. We report a case of a 47-year-old man who developed significant sleep-disordered breathing secondary to opioid use for chronic pain.A sleep study demonstrated a picture of complex sleep apnoea with a prominent central sleep apnoea component. He had no significant improvement with conventional continuous positive airway pressure therapy. However, adaptive servo-ventilation had a dramatic effect on his symptoms and compliance.This case highlights the significant risk of central sleep apnoea with opioid use and illustrates the importance of adaptive servo-ventilation in the management of sleep-disordered breathing secondary to impaired central respiratory drive.
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