相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Microbial nutrient niches in the gut
Fatima C. Pereira et al.
ENVIRONMENTAL MICROBIOLOGY (2017)
Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia
Saumel Ahmadi et al.
NPJ GENOMIC MEDICINE (2017)
SLC6A14 Is a Genetic Modifier of Cystic Fibrosis That Regulates Pseudomonas aeruginosa Attachment to Human Bronchial Epithelial Cells
Michelle Di Paola et al.
MBIO (2017)
Human Intestinal Enteroids: a New Model To Study Human Rotavirus Infection, Host Restriction, and Pathophysiology
Kapil Saxena et al.
JOURNAL OF VIROLOGY (2016)
Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
V. Coothankandaswamy et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology
Jennifer Foulke-Abel et al.
GASTROENTEROLOGY (2016)
Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins
Amanda M. Pattison et al.
INFECTION AND IMMUNITY (2016)
Relationships among CFTR expression, HCO3- secretion, and host defense may inform gene- and cell-based cystic fibrosis therapies
Viral S. Shah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Airway acidification initiates host defense abnormalities in cystic fibrosis mice
Viral S. Shah et al.
SCIENCE (2016)
Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis
Johanna F. Dekkers et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer
Ellappan Babu et al.
BIOCHEMICAL JOURNAL (2015)
Plasma arginine metabolites reflect airway dysfunction in a murine model of allergic airway inflammation
Jeremy A. Scott et al.
JOURNAL OF APPLIED PHYSIOLOGY (2015)
Cystic fibrosis mouse model-dependent intestinal structure and gut microbiome
Mark Bazett et al.
MAMMALIAN GENOME (2015)
Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis
Harriet Corvol et al.
NATURE COMMUNICATIONS (2015)
Loss of Slc26a9 anion transporter alters intestinal electrolyte and HCO3 - transport and reduces survival in CFTR-deficient mice
Xuemei Liu et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation
Stan Pasyk et al.
PROTEOMICS (2015)
Facilitating Structure-Function Studies of CFTR Modulator Sites with Efficiencies in Mutagenesis and Functional Screening
Steven V. Molinski et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
Unraveling the complex genetic model for cystic fibrosis: pleiotropic effects of modifier genes on early cystic fibrosis-related morbidities
Weili Li et al.
HUMAN GENETICS (2014)
The SLC6 transporters: perspectives on structure, functions, regulation, and models for transporter dysfunction
Gary Rudnick et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2014)
The effect of NO-donors on chloride efflux, intracellular Ca2+ concentration and mRNA expression of CFTR and ENaC in cystic fibrosis airway epithelial cells
Igor Oliynyk et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2013)
Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo
Anurag Kumar Singh et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
A functional CFTR assay using primary cystic fibrosis intestinal organoids
Johanna F. Dekkers et al.
NATURE MEDICINE (2013)
The Cystic Fibrosis Intestine
Robert C. De Lisle et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2013)
Ileal smooth muscle dysfunction and remodeling in cystic fibrosis
P. -A. Risse et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Sildenafil Acts as Potentiator and Corrector of CFTR but Might be not Suitable for the Treatment of CF Lung Disease
Geraldine Leier et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2012)
Nitric Oxide and L-Arginine Deficiency in Cystic Fibrosis
Hartmut Grasemann et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Intestinal Smooth Muscle Dysfunction Develops Postnatally in Cystic Fibrosis Mice
Robert C. De Lisle et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2012)
Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis
Lei Sun et al.
NATURE GENETICS (2012)
L-arginine Supplementation Improves Responses to Injury and Inflammation in Dextran Sulfate Sodium Colitis
Lori A. Coburn et al.
PLOS ONE (2012)
Asymmetric Dimethylarginine Contributes to Airway Nitric Oxide Deficiency in Patients with Cystic Fibrosis
Hartmut Grasemann et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
SLC6A14 (ATB0,+) Protein, a Highly Concentrative and Broad Specific Amino Acid Transporter, Is a Novel and Effective Drug Target for Treatment of Estrogen Receptor-positive Breast Cancer
Senthil Karunakaran et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Mouse models of cystic fibrosis: Phenotypic analysis and research applications
Martina Wilke et al.
JOURNAL OF CYSTIC FIBROSIS (2011)
Evidence of Intestinal Inflammation in Patients With Cystic Fibrosis
Steven L. Werlin et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2010)
Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth
Mark P. Rogan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice
Emily M. Bradford et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
Toshiro Sato et al.
NATURE (2009)
Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy
Senthil Karunakaran et al.
BIOCHEMICAL JOURNAL (2008)
Down-regulated in Adenoma Cl/HCO3 Exchanger Couples With Na/H Exchanger 3 for NaCl Absorption in Murine Small Intestine
Nancy M. Walker et al.
GASTROENTEROLOGY (2008)
Human solute carrier SLC6A14 is the β-alanine carrier
Catriona M. H. Anderson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2008)
Amino acid transport across mammalian intestinal and renal epithelia
Stefan Broer
PHYSIOLOGICAL REVIEWS (2008)
Pharmacological modulation of cGMP levels by phosphodiesterase 5 inhibitors as a therapeutic strategy for treatment of respiratory pathology in cystic fibrosis
Jens F. Poschet et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2007)
Down regulation of small intestinal ion transport in PDZK1-(CAP70/NHERF3) deficient mice
Jutta Hillesheim et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Intestinal phenotype of variable-weight cystic fibrosis knockout mice
Juan C. Canale-Zambrano et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
S-nitrosylating agents:: a novel class of compounds that increase cystic fibrosis transmembrane conductance regulator expression and maturation in epithelial cells
Khalequz Zaman et al.
MOLECULAR PHARMACOLOGY (2006)
Relative contribution of genetic and nongenetic modifiers to intestinal obstruction in cystic fibrosis
Scott M. Blackman et al.
GASTROENTEROLOGY (2006)
Mouse as a model of growth retardation in cystic fibrosis
LA Rosenberg et al.
PEDIATRIC RESEARCH (2006)
Increased arginase activity in cystic fibrosis airways
H Grasemann et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2005)
Luminally active, nonabsorbable CFTR inhibitors as potential therapy to reduce intestinal fluid loss in cholera
ND Sonawane et al.
FASEB JOURNAL (2005)
STa and cGMP stimulate CFTR translocation to the surface of villus enterocytes in rat jejunum and is regulated by protein kinase G
F Golin-Bisello et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Clinical manifestations of cystic fibrosis among patients with diagnosis in adulthood
M Gilljam et al.
CHEST (2004)
Characterization of a mouse colonic system B0+ amino acid transporter related to amino acid absorption in colon
S Ugawa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Cloning and functional characterization of a Na+-independent, broad-specific neutral amino acid transporter from mammalian intestine
DP Rajan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2000)
分享论文
