相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Characterization of physiological defects in adult SIRT6-/- mice
Victoria Peshti et al.
PLOS ONE (2017)
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Marjolein P. Baar et al.
CELL (2017)
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2
Huize Pan et al.
CELL RESEARCH (2016)
SPONTANEOUS SINGLE-COPY LOSS OF TP53 IN HUMAN EMBRYONIC STEM CELLS MARKEDLY INCREASES CELL PROLIFERATION AND SURVIVAL.
H. Amir et al.
FERTILITY AND STERILITY (2016)
p53-dependent SIRT6 expression protects Aβ42-induced DNA damage
Eun Sun Jung et al.
SCIENTIFIC REPORTS (2016)
p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency
Jad I. Belle et al.
BLOOD (2015)
Lamin A Is an Endogenous SIRT6 Activator and Promotes SIRT6-Mediated DNA Repair
Shrestha Ghosh et al.
CELL REPORTS (2015)
Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish
Xinyan Lu et al.
CELL DISCOVERY (2015)
SIRT6 Is Required for Normal Retinal Function
Dafne M. Silberman et al.
PLOS ONE (2014)
Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion
Ping Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Chromatin and beyond: the multitasking roles for SIRT6
Site Kugel et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
The guardian: metabolic and tumour-suppressive effects of SIRT6
Batya Lerrer et al.
EMBO JOURNAL (2013)
Senescence and aging: the critical roles of p53
A. Rufini et al.
ONCOGENE (2013)
Lysine-specific modifications of p53: a matter of life and death?
Diana Marouco et al.
ONCOTARGET (2013)
The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism
Carlos Sebastian et al.
CELL (2012)
Surf the Post-translational Modification Network of p53 Regulation
Bo Gu et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)
The Deacetylase Sirt6 Activates the Acetyltransferase GCN5 and Suppresses Hepatic Gluconeogenesis
John E. Dominy et al.
MOLECULAR CELL (2012)
The sirtuin SIRT6 regulates lifespan in male mice
Yariv Kanfi et al.
NATURE (2012)
Sirtuin 6 (SIRT6) rescues the decline of homologous recombination repair during replicative senescence
Zhiyong Mao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
SIRT6 Promotes DNA Repair Under Stress by Activating PARP1
Zhiyong Mao et al.
SCIENCE (2011)
The impact of acetylation and deacetylation on the p53 pathway
Christopher L. Brooks et al.
PROTEIN & CELL (2011)
P53 and aging: A fresh look at an old paradigm
Masha V. Poyurovsky et al.
AGING-US (2010)
SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice
Cuiying Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
被撤回的出版物: Human SIRT6 Promotes DNA End Resection Through CtIP Deacetylation (Publication with Expression of Concern. See vol. 364, pg. 247, 2019) (Publication with Expression of Concern. See vol. 361, pg. 1322, 2018) (Retracted article. See vol. 364, pg. 247, 2019)
Abderrahmane Kaidi et al.
SCIENCE (2010)
Mouse Models of p53 Functions
Guillermina Lozano
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
Tiara L. A. Kawahara et al.
CELL (2009)
Blinded by the Light: The Growing Complexity of p53
Karen H. Vousden et al.
CELL (2009)
Modes of p53 Regulation
Jan-Philipp Kruse et al.
CELL (2009)
Cell cycle-dependent deacetylation of telomeric histone H3 lysine K56 by human SIRT6
Eriko Michishita et al.
CELL CYCLE (2009)
The sirtuin SIRT6 deacetylates H3 K56Ac in vivo to promote genomic stability
Bo Yang et al.
CELL CYCLE (2009)
Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging
George W. Hinkal et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2009)
Using Mice to Examine p53 Functions in Cancer, Aging, and Longevity
Lawrence A. Donehower
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
20 years studying p53 functions in genetically engineered mice
Lawrence A. Donehower et al.
NATURE REVIEWS CANCER (2009)
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
Eriko Michishita et al.
NATURE (2008)
SirT1 fails to affect p53-mediated biological functions
C Kamel et al.
AGING CELL (2006)
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
R Mostoslavsky et al.
CELL (2006)
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
E Michishita et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
I Varela et al.
NATURE (2005)
Genomic instability in laminopathy-based premature aging
BH Liu et al.
NATURE MEDICINE (2005)
Novel p53 inactivators with neuroprotective action: Syntheses and pharmacological evaluation of 2-imino-2,3,4,5,6,7-hexahydrobenzothiazole and 2-imino-2,3,4,5,6,7-hexahydrobenzoxazole derivatives
XX Zhu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism
WZ Duan et al.
ANNALS OF NEUROLOGY (2002)
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
E Langley et al.
EMBO JOURNAL (2002)
p53 mutant mice that display early ageing-associated phenotypes
SD Tyner et al.
NATURE (2002)
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β-peptide
C Culmsee et al.
JOURNAL OF NEUROCHEMISTRY (2001)
分享论文
