期刊
IEEE TRANSACTIONS ON MAGNETICS
卷 51, 期 2, 页码 -出版社
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMAG.2014.2329772
关键词
Magnetic particle imaging; magnetic particle spectroscopy; magnetic particles; tracer performance
资金
- German Federal Ministry of Economics and Technology [FKZ KF3061201UW2]
- DFG [SPP 1681, LU 800/4-1]
- National Institutes of Health [2R42EB013520-02A1, 1RO1EB013689-01/NIBIB]
The drive-field frequency of magnetic particle imaging (MPI) systems plays an important role for system design, safety requirements, and tracer selection. Because the commonly utilized MPI drive-field frequency of 25 kHz might be increased in future system generations to avoid peripheral nerve stimulation, a performance evaluation of tracers at higher frequencies is desirable. We have studied single-core magnetite nanoparticles that were optimized for MPI applications, utilizing magnetic particle spectrometers (MPS) with drive-field frequencies in the range from 1 to 100 kHz. The particles have core diameters of 25 nm and a hydrodynamic size of 77 nm. Measurements in the frequency range above 5 kHz were carried out with a newly designed MPS system. In addition, to exclude possible particle interaction, samples of different concentrations were characterized and compared.
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