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Designed Strategies for Fluorescence-Based Biosensors for the Detection of Mycotoxins

期刊

TOXINS
卷 10, 期 5, 页码 -

出版社

MDPI
DOI: 10.3390/toxins10050197

关键词

mycotoxins; fluorescence assay; biosensors; nanomaterials; fluorescence quenching; food samples

资金

  1. HEC (Higher Education Commission of Pakistan)-NRPU project [5432/Federal/NRPU/RD/HEC/2016]
  2. HEC (Higher Education Commission of Pakistan)-Technology Development Program (TDF) project [028]

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Small molecule toxins such as mycotoxins with low molecular weight are the most widely studied biological toxins. These biological toxins are responsible for food poisoning and have the potential to be used as biological warfare agents at the toxic dose. Due to the poisonous nature of mycotoxins, effective analysis techniques for quantifying their toxicity are indispensable. In this context, biosensors have been emerged as a powerful tool to monitors toxins at extremely low level. Recently, biosensors based on fluorescence detection have attained special interest with the incorporation of nanomaterials. This review paper will focus on the development of fluorescence-based biosensors for mycotoxin detection, with particular emphasis on their design as well as properties such as sensitivity and specificity. A number of these fluorescent biosensors have shown promising results in food samples for the detection of mycotoxins, suggesting their future potential for food applications.

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