期刊
PLOS NEGLECTED TROPICAL DISEASES
卷 12, 期 1, 页码 -出版社
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pntd.0006174
关键词
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资金
- Fonds Wetenschappelijk Onderzoek Vlaanderen [G.0514.14N]
- R. Samuel McLaughlin Manitoba Medical Services Foundation
- University of Manitoba Dean's Fellowship Fund
- National Science Foundation Graduate Research Fellowship
Emergomyces africanus is a thermally dimorphic fungus that causes a systemic mycosis in immunocompromised persons in South Africa. Infection is presumed to follow inhalation of airborne propagules. We developed a quantitative PCR protocol able to detect as few as 5 Es. africanus propagules per day. Samples were collected in Cape Town, South Africa over 50 weeks by a Burkard spore trap with an alternate orifice. We detected Es. africanus in air samples from 34 days (10%) distributed over 11 weeks. These results suggest environmental exposure to airborne Es. africanus propagules occurs more commonly in endemic areas than previously appreciated.
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