Interferon β for Multiple Sclerosis

Despite that the availability of new therapeutic options has expanded the multiple sclerosis (MS) disease-modifying therapy arsenal, interferon beta (IFN-beta) remains an important therapy option in the current decision-making process. This review will summarize the present knowledge of IFN-beta mechanism of action, the overall safety, and the short- and long-term efficacy of its use in relapsing remitting MS and clinically isolated syndromes. Data on secondary progressive MS is also provided, although no clear benefit was identified.