Supramolecular Confinement within Chitosan Nanocomposites Enhances Singlet Oxygen Generation

The synthesis of water-soluble chitosan nanocomposites incorporating BODIPY and the investigation of their photosensitization properties is reported. It was observed that the singlet oxygen generation capability of nanocomposites containing a mixture of BODIPY and iodine-containing molecules are higher than that of the nanocomposites containing BODIPY alone. It is hypothesized that the supramolecular interactions between BODIPY and iodine-containing molecules confined within the nanocomposites lead to the enhanced singlet oxygen generation.