期刊
WORLD NEUROSURGERY
卷 116, 期 -, 页码 279-284出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.wneu.2018.05.158
关键词
CNS HGNET-BCOR; Embryonal tumor; Incision metastasis; Neuroepithelial tumor; PNET; Wound site seeding
资金
- Brain Tumour Charity
- Children with Cancer
- Great Ormond Street Children's Charity
- National Institute for Health Research
- German Children's Cancer Foundation
- MRC [MR/N004272/1, G1100578, G0701018] Funding Source: UKRI
BACKGROUND: Advances in molecular profiling have facilitated the emergence of newly defined entities of central nervous system (CNS) tumor, including CNS high-grade neuroepithelial tumor with BCOR alteration (CNS HGNET-BCOR). Relatively little is known about the clinical behavior of these newly characterized tumors. CASE DESCRIPTION: We describe a pediatric male patient with CNS HGNET-BCOR, who developed seeding of the tumor into the site of the surgical wound within months of surgery and who underwent resection of a residual posterior fossa tumor. CONCLUSIONS: This case emphasizes 3 important points. First, CNS HGNET-BCOR can be aggressive tumors that necessitate close clinical and radiologic surveillance. Second, surveillance imaging in such cases should incorporate the surgical incision site into the field of view, and this should be closely scrutinized to ensure the timely detection of wound site seeding. Third, wound site seeding may still occur despite the use of meticulous surgical techniques.
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