相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
Kai Kaarniranta et al.
CELL BIOLOGY AND TOXICOLOGY (2017)
Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina
Marcus Karlstetter et al.
EMBO MOLECULAR MEDICINE (2017)
Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration
Alessandro Iannaccone et al.
EXPERIMENTAL EYE RESEARCH (2017)
Local complement activation in aqueous humor in patients with age-related macular degeneration
T. Schick et al.
EYE (2017)
Microglia- derived IL-1β promotes chemokine expression by Muller cells and RPE in focal retinal degeneration
Riccardo Natoli et al.
MOLECULAR NEURODEGENERATION (2017)
Comprehensive analysis of mouse retinal mononuclear phagocytes
Anika Lueckoff et al.
NATURE PROTOCOLS (2017)
Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damage
Raquel Boia et al.
CELL DEATH & DISEASE (2017)
Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal Degeneration
Riccardo Natoli et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2017)
Activated microglia trigger inflammasome activation and lysosomal destabilization in human RPE cells
Christopher Nebel et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Age-related macular degeneration: genome-wide association studies to translation
James R. M. Black et al.
GENETICS IN MEDICINE (2016)
A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants
Lars G. Fritsche et al.
NATURE GENETICS (2016)
Inflammation and its role in age-related macular degeneration
Anu Kauppinen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Targeting the complement system for the management of retinal inflammatory and degenerative diseases
Heping Xu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
How does adenosine control neuronal dysfunction and neurodegeneration?
Rodrigo A. Cunha
JOURNAL OF NEUROCHEMISTRY (2016)
Inflammasome priming increases retinal pigment epithelial cell susceptibility to lipofuscin phototoxicity by changing the cell death mechanism from apoptosis to pyroptosis
Carolina Brandstetter et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2016)
Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure-induced transient ischemic injury
Maria H. Madeira et al.
TRANSLATIONAL RESEARCH (2016)
Higher plasma levels of complement C3a, C4a and C5a increase the risk of subretinal fibrosis in neovascular age-related macular degeneration
Judith Lechner et al.
IMMUNITY & AGEING (2016)
Methods for culturing retinal pigment epithelial cells: a review of current protocols and future recommendations
Aaron H. Fronk et al.
JOURNAL OF TISSUE ENGINEERING (2016)
Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma
Maria H. Madeira et al.
SCIENTIFIC REPORTS (2016)
NLRP3 Upregulation in Retinal Pigment Epithelium in Age-Related Macular Degeneration
Yujuan Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium
Jingyu Yao et al.
AUTOPHAGY (2015)
Parainflammation, chronic inflammation, and age-related macular degeneration
Mei Chen et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2015)
Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage
Carolina Brandstetter et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2015)
Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure
Maria H. Madeira et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia
Alexander Aslanidis et al.
JOURNAL OF NEUROINFLAMMATION (2015)
NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration
Jiangyuan Gao et al.
MEDIATORS OF INFLAMMATION (2015)
Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases
Maria H. Madeira et al.
MEDIATORS OF INFLAMMATION (2015)
Retinal microglia: Just bystander or target for therapy?
Marcus Karlstetter et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2015)
NLRP3 Inflammasome and Pathobiology in AMD
Lucia Celkova et al.
JOURNAL OF CLINICAL MEDICINE (2015)
Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis
Alessandro Iannaccone et al.
PLOS ONE (2015)
Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells
Niina Piippo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis
Marcus Karlstetter et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Role of Microglia Adenosine A(2A) Receptors in Retinal and Brain Neurodegenerative Diseases
Ana R. Santiago et al.
MEDIATORS OF INFLAMMATION (2014)
Synthesis and Propagation of Complement C3 by Microglia/Monocytes in the Aging Retina
Matt Rutar et al.
PLOS ONE (2014)
Versatility of the complement system in neuroinflammation, neurodegeneration and brain homeostasis
Franca Orsini et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
Wan Ling Wong et al.
LANCET GLOBAL HEALTH (2014)
Photoreceptor Proteins Initiate Microglial Activation via Toll-like Receptor 4 in Retinal Degeneration Mediated by All-trans-retinal
Hideo Kohno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
A2E accumulation influences retinal microglial activation and complement regulation
Wenxin Ma et al.
NEUROBIOLOGY OF AGING (2013)
Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis
Amanda Sierra et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Adenosine is required for sustained inflammasome activation via the A2A receptor and the HIF-1α pathway
Xinshou Ouyang et al.
NATURE COMMUNICATIONS (2013)
Association between Polymorphisms of Complement Pathway Genes and Age-Related Macular Degeneration in a Chinese Population
Lin Wu et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)
NLRP3 Inflammasome Activation in Retinal Pigment Epithelial Cells by Lysosomal Destabilization: Implications for Age-Related Macular Degeneration
Wen Allen Tseng et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2013)
Genetic variation in complement regulators and susceptibility to age-related macular degeneration
Valentina Cipriani et al.
IMMUNOBIOLOGY (2012)
Inhibiting Alternative Pathway Complement Activation by Targeting the Factor D Exosite
Kenneth J. Katschke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira et al.
NATURE IMMUNOLOGY (2011)
Human Retinal Pigment Epithelium Cells as Functional Models for the RPE In Vivo
Zsolt Ablonczy et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Analysis of Complement Expression in Light-Induced Retinal Degeneration: Synthesis and Deposition of C3 by Microglia/Macrophages Is Associated with Focal Photoreceptor Degeneration
Matt Rutar et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
Therapeutic potential of complement modulation
Eric Wagner et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
Don H. Anderson et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2010)
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Luigi Franchi et al.
NATURE IMMUNOLOGY (2009)
Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD
Wenxin Ma et al.
PLOS ONE (2009)
Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms
Liqun Yu et al.
ANNALS OF NEUROLOGY (2008)
Activation of microglia with zymosan promotes excitatory amino acid release via volume-regulated anion channels: the role of NADPH oxidases
Timothy J. Harrigan et al.
JOURNAL OF NEUROCHEMISTRY (2008)
The natural history and prognosis of neovascular age-related macular degeneration
Tien Wong et al.
OPHTHALMOLOGY (2008)
Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
Jilin Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Drusen complement components C3a and C5a promote choroidal neovascularization
M Nozaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Adenosine A2A receptor stimulation potentiates nitric oxide release by activated microglia
J Saura et al.
JOURNAL OF NEUROCHEMISTRY (2005)
The role of apoptosis in age-related macular degeneration
JL Dunaief et al.
ARCHIVES OF OPHTHALMOLOGY (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)