期刊
JOURNAL OF FUNCTIONAL BIOMATERIALS
卷 3, 期 2, 页码 -出版社
MDPI
DOI: 10.3390/jfb3020349
关键词
drug eluting stent; plasma electrolytic oxidation; titanium oxide layer; stainless steel; surface porosity
资金
- Project NEXTREAM under the research program of the BioMedical Materials Institute [P1.02]
- Dutch Ministry of Economic Affairs, Agriculture and Innovation
- Nederlandse Hartstichting
In this study, a porous oxide layer was formed on the surface of 316L stainless steel (SS) by combining Ti magnetron sputtering and plasma electrolytic oxidation (PEO) with the aim to produce a polymer-free drug carrier for drug eluting stent (DES) applications. The oxidation was performed galvanostatically in Na3PO4 electrolyte. The surface porosity, average pore size and roughness varied with PEO treatment duration, and under optimum conditions, the surface showed a porosity of 7.43%, an average pore size of 0.44 mu m and a roughness (Ra) of 0.34 mu m. The EDS analyses revealed that the porous layer consisted of Ti, O and P. The cross-sectional morphology evidenced a double-layer structure, with a porous titania surface and an un-oxidized dense Ti film towards the interface with 316L SS. After the PEO treatment, wettability and surface free energy increased significantly. The results of the present study confirm the feasibility of forming a porous TiO2 layer on stainless steel by combining sputtering technology and PEO. Further, the resultant porous oxide layer has the potential to be used as a drug carrier for DES, thus avoiding the complications associated with the polymer based carriers.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据