期刊
NUCLEAR MEDICINE AND MOLECULAR IMAGING
卷 46, 期 2, 页码 129-133出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s13139-012-0133-0
关键词
Ga-68 DOTA-TOC PET/CT; Ga-68DOTA-TATE PET/CT; Ga-68DOTA-NOC PET/CT; von Hippel-Lindau disease; Hemangioblastoma; Pheochromocytoma
Von Hippel-Lindau (VHL) disease is a dominantly inherited familial cancer syndrome with a variety of benign and malignant tumors such as retinal and central nervous system hemangioblastomas, endolymphatic sac tumors, renal cysts and tumors, pancreatic cysts and tumors, pheochromocytomas, and epididymal cystadenomas. Cross-sectional modalities (computed tomography and magnetic resonance imaging) as well as ultrasound play a major role in the initial evaluation and follow-up of the various manifestations of VHL disease. Ga-68-labeled somatostatin receptor analogs already have a significant role in the diagnosis, staging, and therapy management of neuroendocrine neoplasms and neural crest tumors. Herein, we report a case presenting a variety of malignancies in VHL and showing the usefulness of Ga-68 somatostatin receptor PET/CT as a one-stop-shop imaging modality in the management of VHL disease.
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